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| 1 | 肝脏少见肿瘤的影像学表现显示文摘肝脏是各类原发及继发肿瘤发生的常见器官,组织学类型多种多样,但部分肿瘤类型较少见,CT和MRI可显示肝内病变大小、形态、密度或信号、周围组织关系及肿瘤血供情况,同时MRI具有较高的软组织分辨率。综合运用CT和MRI检查,总结肝脏少见肿瘤的影像学表现,旨在提高对肝脏少见肿瘤的诊断水平,更好的发挥影像学在肝脏肿瘤诊疗中的作用。 | 李欣明 全显跃 覃淑萍 | 2016 | 临床肝胆病杂志2016，32，12： | 7 |
| 2 | Inflammatory myofibroblastic tumor of the liver:A case report and review of literature显示文摘BACKGROUND Inflammatory myofibroblastic tumors of the liver(IMTL)are extremely rare neoplasms and very little is known about their clinical presentation,pathogenesis,and biological behavior.Due to their absolute rarity,it is almost impossible to obtain a definite diagnosis without histological examination.Because of their intermediate biological behavior with the risk for local recurrence and metastases,surgical resection is recommend whenever IMTL is suspect.CASE SUMMARY We herein present a case of an otherwise healthy 32-year-old woman who presented with intermittent fever,unclear anemia,malaise and right flank pain 4 mo postpartum.The liver mass in segment IVa/b was highly FDG avid in the positron emission tomography-computed tomography.Hepatic resection was performed achieving a negative resection margin and an immediate resolution of all clinical symptoms.Histological analysis diagnosed the rare finding of an inflammatory myofibroblastic tumor of the liver and revealed cytoplasmic anaplastic lymphoma kinase expression by immunohistochemistry.Twelve months follow-up magnetic resonance imaging showed no recurrence and no metastases in the fully recovered patient.CONCLUSION IMTLs are extremely rare and difficult to diagnose.Due to their intermediate biological behavior,surgical resection should be perform whenever feasible and patients should be followed-up in order to detect recurrence and metastasis as early as possible. | Alexandra Filips Martin H Maurer Matteo Montani Guido Beldi Anja Lachenmayer | 2020 | World Journal of Hepatology2020，12，4： | 4 |
| 3 | 肝脏增生性瘤样病变诊疗研究进展显示文摘肝脏增生性瘤样病变是一类多由炎性反应、感染、发育异常或其他不明原因导致肝实质、胆管或间质细胞出现异常增生而形成的局部实性瘤样病变,属于肝占位良性病变,其病理学检查以细胞增生为主要表现,但无肿瘤细胞的异型性[1]。根据肝脏瘤样病变病理学分类[2],该类疾病临床上常分为局灶性结节性增生(FNH)、炎性假瘤(IPT)、肝脏腺瘤样增生(ANH)、局灶性脂肪变(FFC)、肝淋巴样组织增生、肝结核等,以肝占位性病变为主要表现,易与肝血管瘤、肝囊肿等良性肿瘤区分,但难以与原发性肝癌、转移性肝癌相鉴别。同时,该类疾病发病率较低,诊治经验较少,临床不易确诊,治疗尚存争议。如何提高该类疾病的诊疗及合理制订个体化治疗方案,是肝脏外科面临的难题。作者先将常见肿瘤增生性瘤样病变综述如下。 | 徐伟 刘作金 | 2018 | 现代医药卫生2018，34，17： | 3 |
| 4 | 肝胆炎性肌纤维母细胞瘤的临床病理分析显示文摘炎性肌纤维母细胞瘤(inflammatory myofibroblastic tumor,IMT)是一种罕见的间叶源性肿瘤,发病部位广泛,常见于肺脏,发生于肝胆系统较为罕见.我们收集了10例经病理证实的肝胆IMT患者的临床资料.本文回顾性分析了患者的临床诊疗情况、临床病理特征、免疫组化及预后,并复习相关文献. | 高鹏飞 舒曼 | 2017 | 中华肝胆外科杂志2017，23，5： | 2 |
| 5 | Complicated course of biliary inflammatory myofibroblastic tumor mimicking hilar cholangiocarcinoma:A case report and literature review显示文摘BACKGROUND The inflammatory myofibroblastic tumor(IMT)is a rare,idiopathic,usually benign,mass-forming disease with myofibroblastic proliferation and a varying amount of inflammatory cells.Although it can affect various organs,the biliary tract is a rare localization of primary IMT,clinically,endoscopically and radiologically imitating cholangiocarcinoma.The treatment options are based only on clinical practice experience.CASE SUMMARY A 70-year-old woman was referred to our center due to progressive fatigue,weight loss,abdominal pain,night sweats,and elevated liver enzymes.Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography(ERCP)revealed proximal common hepatic duct and hilar biliary strictures extending bilaterally to lobular bile ducts.Although initial clinical,endoscopic and radiological signs were typical for hilar cholangiocarcinoma,histological examination showed no signs of malignancy.In total,8 biopsies using different approaches were performed(several biopsies from dominant stricture during ERCP and direct cholangioscopy;ultrasound-guided liver biopsy;diagnostic laparoscopy with liver and lymph node biopsies).Histological examination revealed signs of IMT,and the final diagnosis of biliary IMT was stated.Although IMT is usually a benign disease,in our case,it was complicated.All pharmacological treatment measures were ineffective.The patient still needs permanent stenting,suffers from recurrent infections and mechanical jaundice.Despite that,the patient already survived 24 mo.CONCLUSION IMT presenting with hilar biliary strictures is a unique diagnostic and clinical challenge as it is indistinguishable from cholangiocarcinoma,and there are no evidence-based treatment options.Our goal is to increase the understanding of this rare disease and its possible course. | Sandra Strainiene Kotryna Sedleckaite Juozas Jarasunas Ilona Savlan Juozas Stanaitis Ieva Stundiene Tomas Strainys Valentina Liakina Jonas Valantinas | 2021 | World Journal of Clinical Cases2021，9，21： | 1 |
| 6 | CT对肝炎性肌纤维母细胞瘤的诊断价值显示文摘目的分析肝炎性肌纤维母细胞瘤的CT表现,提高影像诊断准确率。方法选择2013年1月至2018年8月南京医科大学附属南京医院8例经手术或穿刺病理确诊的肝炎性肌纤维母细胞瘤患者,其中男性4例,女性4例;年龄50~65岁,平均年龄57.5岁。行CT平扫及增强扫描,总结CT影像特点。结果 6例显示不均匀渐进性强化,以轻、中度强化为主,病灶中央部分强化程度低于边缘部分;1例呈门静脉期边缘轻度环状强化,1例显示不明显轻度分隔强化,另1例合并有门静脉左支闭塞,并于周围可见侧支循环产生。结论肝炎性肌纤维母细胞瘤的CT表现具有一定特点,但仍需与肝内恶性肿瘤相鉴别,确诊依靠肝穿刺或手术行病理学检查和免疫组织化学检查。 | 施梦烨 王丽萍 | 2019 | 生物医学工程与临床2019，23，2： | 0 |
| 7 | Laparoscopic treatment of inflammatory myofibroblastic tumor in liver: A case report显示文摘BACKGROUND Inflammatory myofibroblastic tumor in the liver(IMTL) is a rare borderline mesenchymal tumor.Neither clinical symptoms nor laboratory tests have absolute specificity for the diagnosis of IMTL,and imaging also lacks obvious specificity.Although there are sporadic reports of recurrence after surgical treatment,surgical resection is the mainstay of treatment.CASE SUMMARY A 29-year-old man complained of general weakness,slight discomfort in the upper abdomen,with a history of upper respiratory tract infection for 1 wk before admission.Plain and enhanced upper abdominal magnetic resonance imaging showed a mass in liver segments Ⅱ and Ⅲ(48 mm × 53 mm).He was treated by laparoscopic left lateral segmentectomy.Postoperative pathological examination with hematoxylin and eosin staining suggested that the mass in liver segments Ⅱ and Ⅲ was IMTL.During 21 mo postoperative follow-up,no obvious residual or recurrent lesions were observed.CONCLUSION There is a risk of malignant degeneration in IMTL.The principal choice of treatment is laparoscopic left lateral segmentectomy. | Yang-Yang Li Jin-Feng Zang Chi Zhang | 2022 | World Journal of Clinical Cases2022，10，32： | 0 |
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