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| 1 | Preparation of low molecular weight Sargassum fusiforme polysaccharide and its anticoagulant activity显示文摘Heparin has been used as an anticoagulant drug for many years, but it has significant side ef fects. In the search for good substitutes, low molecular weight(MW) polysaccharides from S argassum fusiforme have been examined and confi rmed to possess biological activities. Here, S. fusiforme polysaccharides(SFP) were extracted and subjected to a hydrogen peroxide(H_2O_2) oxidation method for the preparation of low-MW SFP(LSFP). The effects of temperature, pH, and H_2O_2 concentration on the degradation process were also examined. Several LSFP of 36, 9, 5.7, and 2.7 kDa were obtained under different conditions, and their anticoagulant activities studied in vitro. The results showed that SFP and LSFP prolonged activated partial thromboplastin(APTT), prothrombin(PT) and thrombin times(TT) significantly, indicating that these low MW polysaccharides possessed anticoagulant activity in the intrinsic, extrinsic, and common coagulation pathways. As these ef fects were related to the MW of the polysaccharides in APTT and TT but not in PT, the contents of the monosaccharide fucose and sulfate and the polysaccharide MW could have exerted combined ef fects. The details of this mechanism require further verifi cation. | 孙雨豪 陈晓琳 刘松 于华华 李荣锋 王雪芹 秦玉坤 李鹏程 | 2018 | Journal of Oceanology and Limnology2018，36，3： | 8 |
| 2 | 中药继承与创新中几个问题的思考显示文摘中医药作为人类历史上历史最为悠久、使用人数最多、理论体系最完整、药物品种最丰富的传统医学,为人类的发展与进步起到了巨大的作用。将从复方中药研究的现状与前景、大中药概念与中药的多样性、中医药个性化诊疗与中药质量标准化、防重于治与中药养生科学、影响中药疗效的几个关键因素和让中医药走入绅士层面6个方面进行讨论与思考,以期与志同道合者共同为推进中医药的发展贡献微薄之力。 | 刘延泽 谢晶曦 | 2017 | 中草药2017，48，7： | 7 |
| 3 | 羊栖菜冬季南养的初步研究显示文摘采用浮筏式养殖方式于2014年11月—2015年3月,在海南省儋州市海头镇海区进行了羊栖菜的冬季南养试验,记录了其生长规律,并比较了不同养殖水深对羊栖菜生长的影响。结果显示:在营养生长的过程中,藻体长度以趋近于线性的方式增长;而质量的增加则表现出由慢到快的规律。在水深60 cm的条件下羊栖菜生长最快;本次试验羊栖菜干品产量为340kg/亩,比浙江洞头养殖的羊栖菜平均产量增长约42.9%,而养殖周期缩短了一半以上。试验结果不仅证实了在海南进行羊栖菜冬季南养的可行性,而且显示出周期短、产量高的优势,为建立羊栖菜'冬季南养'的新型养殖模式提供了依据和参考。 | 邹潇潇 林勇 朱军 黄惠琴 鲍时翔 | 2017 | 水产养殖2017，38，1： | 0 |
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