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    题名 作者 年代 出处 被引量
1Chimeric antigen receptor (CAR)-modified natural killer cell-based immunotherapy and immunological synapse formation in cancer and HIV显示文摘Dongfang Liu Shuo Tian Kai Zhang Wei Xiong Ndongala Michel Lubaki Zhiying Chen Weidong Han 2017Protein & Cell2017,8,12:11
2Cancer immunotherapy显示文摘Unprecedented progress has seen made in the last decade in the fi eld of cancer immunotherapy.The recent approval of nivolumab(Opdivo),the fi rst anti-programmed cell death-1(PD-1)antibody,for metastatic melanoma in Japan,marked a milestone in the rapidly advancing fi eld of cancer immunotherapy.Nivolumab togetherLi Yan Helen X.Chen 2014Chinese Journal of Cancer2014,33,9:10
3Stem cell-derived exosomes: roles (I)CrossMarkin stromal remodeling, tumor progression,and cancer immunotherapy显示文摘Stem cells are known to maintain sternness at least in part through secreted factors that promote stem-like phenotypesin resident cells. Accumulating evidence has clarified that stem cells release nano-vesicles, known as exosomes,which may serve as mediators of cell-to-cell communication and may potentially transmit stem cell phenotypes torecipient cells, facilitating stem cell maintenance, differentiation, self-renewal, and repair. It has become apparent thatstem cell-derived exosomes mediate interactions among stromal elements, promote genetic instability in recipientcells, and induce malignant transformation. This review will therefore discuss the potential of stem cell-derivedexosomes in the context of stromal remodeling and their ability to generate cancer-initiating cells in a tumor nicheby inducing morphologic and functional differentiation of fibroblasts into tumor-initiating fibroblasts. In addition, theimmunosuppressive potential of stem cell-derived exosomes in cancer immunotherapy and their prospective applicationsin cell-free therapies in future translational medicine is discussed.2015Chinese Journal of Cancer2015,34,12:5
4哺乳动物免疫球蛋白基因及其表达机制研究进展显示文摘动物免疫球蛋白的基因序列、结构类型、功能以及其多样性的机制一直国内外学者关注焦点。目前对于免疫球蛋白基因及其多样性表达机制的研究多数是以人类或者小鼠为对象,该文将论述猪、牛、羊、骆驼和家兔的免疫球蛋白基因结构及其表达机制,探究不同哺乳动物免疫球蛋白基因表达的特点,以期为动物免疫方面和抗病育种的研究提供参考。陶晓钊 薄欣宇 段树楠 任战军 董响贵 王淑辉 2023中国畜禽种业2023,19,8:0
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