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| 1 | Involvement of cholangiocyte proliferation in biliary fibrosis显示文摘Cholangiocytes are the epithelial cells that line the biliary tree.In the adult liver,they are a mitotically dormant cell population,unless ductular reaction is triggered by injury.The ability of cholangiocytes to proliferate is important in many different human pathological liver conditions that target this cell type,which are termed cholangiopathies(i.e.primary biliary cirrhosis,primary sclerosing cholangitis and biliary atresia).In our article,we provide background information on the morphological and functional heterogeneity of cholangiocytes,summarize what is currently known about their proliferative processes,and briefly describe the diseases that target these cells.In addition,we address recent findings that suggest cholangiocyte involvement in epithelial-to-mesenchymal transformation and liver fibrosis,and propose directions for future studies. | Sally Priester Candace Wise Shannon S Glaser | 2010 | World Journal of Gastrointestinal Pathophysiology2010，1，2： | 10 |
| 2 | 胆道外科基础研究的现状与方向显示文摘进入21世纪,随着分子生物学、分子遗传学、医学影像学等相关科学的发展,胆道外科基础研究取得了令人瞩目的成果,但面对常见、多发的胆结石,其成因尚未完全清楚,有效预防问题也急需解决;针对日益增多的胆道肿瘤,如何做到早期诊断、提高治疗效果也是胆道外科的一大难题;有关肝移植术后缺血型胆道病变的防治、胆管细胞与胆管血供在胆道外科疾病发生和防治中的重要作用、Oddi括约肌在胆道重建中的重要作用等问题也在不断涌现. | 张宗明 | 2007 | 中国现代普通外科进展2007，10，2： | 5 |
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