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| 1 | 儿童孤独症谱系障碍评估工具的研究进展显示文摘目的本文主要回顾了国内外儿童孤独症谱系障碍常用的评估工具,分析了各类工具的基本内容、信效度、适用范围及应用情况等,并据此提出我国在此领域的研究方向,旨在为儿童孤独症谱系障碍的临床诊断、筛查和科学研究提供可参考的依据。 | 金映彤 陈苏琴 包韵歆 周美珍 | 2021 | 护理实践与研究2021，18，9： | 6 |
| 2 | 孤独症谱系障碍与智力障碍共患与鉴别研究进展显示文摘孤独症谱系障碍(autism spectrum disorder,ASD)是一组以社会交往及交流障碍、狭隘兴趣及重复刻板行为(restricted and repetitive behaviors,RRB)为核心症状的神经发育性疾病。智力障碍(intellectual disability,ID)是指18岁以前发育过程中出现的认知及社会适应能力障碍,其中ID多用于5岁以上儿童,而5岁以下的婴幼儿因其智力测定不可靠。 | 杨育林 代英 | 2022 | 中国实用儿科杂志2022，37，4： | 6 |
| 3 | The First National Prevalence of Autism Spectrum Disorder in China显示文摘Autism spectrum disorder (ASD) is a complex developmental disability characterized by impaired social interaction and communication,restricted interests,and stereotypical behaviors [1,2].In addition to these core diagnostic features,children with ASD frequently present with a host of associated behavioral issues,such as intellectual disability and epilepsy,as well as feeding and sleep problems.The prevalence of ASD in the United States is about 1/59,with a significantly higher proportion in males [3].Therefore,ASD is no longer a rare disorder. | Zi Chao Zhang Junhai Han | 2020 | Neuroscience Bulletin2020，36，9： | 5 |
| 4 | Structural,Functional,and Molecular Imaging of Autism Spectrum Disorder显示文摘Autism spectrum disorder(ASD)is a heterogeneous neurodevelopmental disorder associated with both genetic and environmental risks.Neuroimaging approaches have been widely employed to parse the neurophysiological mechanisms underlying ASD,and provide critical insights into the anatomical,functional,and neurochemical changes.We reviewed recent advances in neuroimaging studies that focused on ASD by using magnetic resonance imaging(MRI),positron emission tomography(PET),or single-positron emission tomography(SPECT).Longitudinal structural MRI has delineated an abnormal developmental trajectory of ASD that is associated with cascading neurobiological processes,and functional MRI has pointed to disrupted functional neural networks.Meanwhile,PET and SPECT imaging have revealed that metabolic and neurotransmitter abnormalities may contribute to shaping the aberrant neural circuits of ASD.Future large-scale,multi-center,multimodal investigations are essential to elucidate the neurophysiological underpinnings of ASD,and facilitate the development of novel diagnostic biomarkers and better-targeted therapy. | Xiaoyi Li Kai Zhang Xiao He Jinyun Zhou Chentao Jin Lesang Shen Yuanxue Gao Mei Tian Hong Zhang | 2021 | Neuroscience Bulletin2021，37，7： | 4 |
| 5 | 几种常见儿童孤独症谱系障碍筛查及诊断量表的比较研究显示文摘近年来,儿童孤独症谱系障碍(ASD)患病率逐年升高,需要更加科学有效的量表来进行儿童ASD的筛查和诊断。本文通过对儿童ASD筛查及诊断量表所适用的年龄、评估方式、计分方法、评定标准和基本内容进行归纳、整理,从多维度分析、总结常用的一级筛查量表、二级筛查量表和诊断量表的特点、用途、灵敏度和特异度方面的优缺点和差异。基于专业使用与家庭使用的双视角对ASD量表进行深层次地解析与重构,探索可用于儿童ASD筛查和诊断的新方法,旨在缓解专业人员资源短缺的问题,提高儿童ASD筛查与诊断的准确性,并降低误诊率和假阳性率,为儿童ASD早期干预数据的收集以及后期治疗提供可靠的科学依据。 | 蔡郑婷 胡连信 王泽峰 谢广东 林贤伟 | 2022 | 中国全科医学2022，25，24： | 3 |
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