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| 1 | 抗精子抗体介导不育的再认识显示文摘男、女性体内抗精子抗体(ASA)可以降低生育力,导致不育。但ASA介导免疫不育的关系非常复杂,目前认识仍有限。本文基于笔者30多年ASA的检测实践及以往文献审读,围绕ASA检测、ASA对睾丸精子发生、精索静脉曲张、流产的影响,以及宫腔内人工授精(IUI)、体外受精(IVF)、卵胞质内精子注射(ICSI)治疗ASA不育患者的疗效进行了评价;并针对当前ASA的阳性率、抗体水平、一般治疗效果等问题提出看法,以期增进ASA与生殖效应相互关系的深入认识。 | 朱伟杰 | 2017 | 生殖与避孕2017，37，1： | 14 |
| 2 | Hemospermia is not associated with the production of antisperm antibody显示文摘Objective To investigate whether hemospermia is involved in the production of antisperm antibodies(ASA).Methods A total of 40 males with hemospermia were enrolled in this study. These males were divided into 3 groups according to their fertile status: 18 cases were patients who visited the infertility clinic(group A), 8 had fertility(group B), and 14 did not know their fertile status(group C). Semen samples were collected and ASA levels were detected by the direct immunobead test(D-IBT). Leukocytes in semen were assessed by the peroxidase assay.Results None of these males with hemospermia were found to display significant levels of ASA in the 3 groups. The number of cases who had increased levels of leukocytes in the semen samples of groups A, B and C were 15(83.3%), 6(75.0%) and 12(85.7%),respectively.Conclusion Hemospermia is not associated with the production of ASA. It is worth noting that the leukocyte levels are increased in semen of males with hemospermia. | Yue-juan ZHANG Rui HUANG Dong CHEN Bao-guo XIE Wei-jie ZHU | 2015 | Journal of Reproduction and Contraception2015，26，4： | 1 |
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