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    题名 作者 年代 出处 被引量
1Direct amination of pyrimidin-2-yl tosylates with aqueous ammonia under metal-free and mild conditions显示文摘A metal-free synthesis of pyrimidine functionalized primary amines via direct amination of pyrimidin-2-yl tosylate with aqueous ammonia has been developed under mild conditions. The desired products pyrimidin-2-amines can be generated in excellent yields in PEG-400, without any catalysts or other additives.Hai-Peng Gong Yue Zhang Yu-Xia Da Zhang Zhang Zheng-Jun Quan Xi-Cun Wang 2015Chinese Chemical Letters2015,26,6:0
2Synthesis,characterization and antibacterial screening of some novel 1,2,4-triazine derivatives显示文摘A new series of 1, 2, 4-triazine derivatives possessing indole nucleus were synthesized with an aim to explore their effect on in vitro growth of microorganisms causing microbial infection. In vitro antimicrobial activity was performed against S. aureus, S. epidermidis, P. mirabilis and E. coli using disk diffusion method. The MIC was detected using the double dilution method. The results were compared by calculating percent inhibition area/mg of the compounds with the standard drug 'Ciprofloxacin'.Selected compounds were evaluated for toxic effects using human hepatocellular carcinoma(HepG2) cell line by MTT-assay. Results revealed that some compounds of the series were found to exhibit better activity with less toxicity thanMohammad Arshad Abdul Roouf Bhat Kwon Kang Hoi Inho Choi Fareeda Athar 2017Chinese Chemical Letters2017,28,7:0
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