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| 1 | 苯并(a)芘的生殖内分泌干扰作用研究进展显示文摘苯并(a)芘[Benzo(a) pyrene,BaP]是国际癌症研究机构(IARC)确定的Ⅰ类致癌物[1],因其来源广泛,是一种普遍存在于空气颗粒物、水、土壤及沉积物等环境介质中的持久性有机污染物[2-3],是多环芳烃类(PAHs)中最具代表性的一类物质,是一种可疑的环境内分泌干扰物(environmental endocrine dis-ruptors,EEDs)。 | 潘阳 | 2021 | 中国卫生工程学2021，20，3： | 1 |
| 2 | 多氯联苯对甲状腺影响的研究进展显示文摘多氯联苯是典型的持久性有机干扰物,其内分泌干扰效应受到越来越多的关注。多氯联苯可能通过多种机制干扰甲状腺激素稳态,但目前对其中具体机制仍不清楚,故进一步深入研究多氯联苯对甲状腺的影响,有助于提高防治甲状腺疾病的意识及策略。 | 朱辉 陈国芳 徐书杭 刘超 蔡可英 | 2015 | 江苏医药2015，41，3： | 0 |
| 3 | Exposure to bisphenol a and risk of developing type 2 diabetes: A mini review显示文摘Type 2 Diabetes Mellitus(T2DM)is a metabolic disorder,which results from a defect in insulin production,impaired insulin action or both.It is now regarded as one of the major non-communicable diseases on the rise worldwide.This exponential rise in incidence of T2DM,especially in children,adolescents and women of childbearing age,may be partly attributed to diet,lifestyle and genetic variation.However,the effects of exposure to environmental contaminants,such as endocrine disrupting compounds(EDCs),cannot be neglected.Bisphenol A(BPA)is an endocrine disruptor,and one of the large volume chemicals produced worldwide.BPA is widely used additive in the manufacture of polycarbonate plastic and epoxy resins.BPA can either be released into the environment during the production process and/or by leaching from the finished products.This high production volume(HPV)chemical is ubiquitous in the environment and consistently high levels of BPA in human subjects(in serum as well as in urine)have been reported.Due to endocrine disrupting properties of BPA,owing to its affinity for the estrogen receptors,its potential metabolic effects have been an interest for researchers worldwide.Therefore,the objective of this review is to assess the exposure to BPA in pregnant women and children and its probable role in the development of T2DM. | Shabana Siddique Gong Zhang Cariton Kubwabo | 2020 | Emerging Contaminants2020，6，1： | 0 |
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