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| 1 | 重复经颅磁刺激用于精神分裂症中安全性及可行性显示文摘目的探讨重复经颅磁刺激用于精神分裂症中安全性及可行性。方法运用随机抽样方选取我院2013-01-2014-09收治的60例精神分裂症患者,依据治疗方法将患者分为研究组(n=30)和对照组(n=30)。对照组患者给予假刺激方案治疗,研究组给予重复经颅磁刺激治疗。结果研究组阳性和阴性症状评分均显著低于对照组(P<0.05),精神症状改善时间和住院时间均显著短于对照组(P<0.05),治疗的总有效率93.3%(28/30)显著高于对照组70.0%(21/30)(P<0.05),不良反应发生率13.3%(4/30)显著低于对照组33.3%(10/30),P<0.05。结论重复经颅磁刺激用于精神分裂症中安全可行,值得推广。 | 郭丽 | 2016 | 中国实用神经疾病杂志2016，19，2： | 14 |
| 2 | 精神分裂症患者的情绪体验、表达与调节显示文摘愉快情绪体验能力的下降,即快感缺失,是精神分裂症患者的症状表现之一。本研究综述从情绪加工(情绪调节与表达)的角度,来探讨精神分裂症患者的快感缺失。分析表明,精神分裂症患者期待性愉快体验的缺失与适应不良的情绪调节策略、情绪表达缺损有关。未来的研究需要系统地对比精神分裂症患者与健康人群在情绪体验、表达与调节方面的差异,在此基础上,为改善快感缺失的临床干预方法,提供参考借鉴意义。 | 倪珂 邹颖敏 陈楚侨 | 2017 | 中国心理卫生杂志2017，31，6： | 13 |
| 3 | 综合性心理行为干预对慢性精神分裂患者认知功能的效果分析显示文摘目的:研究综合性心理行为干预对慢性精神分裂患者的认知功能影响。方法:选取2012年2月-2013年6月笔者所在医院接受治疗的130例慢性精神分裂患者为研究对象。按照随机数字表法分为观察组和对照组,每组65例。两组均进行药物治疗,观察组病患在药物治疗的基础上采用综合性心理行为干预治疗,对照组病患采用简单的心理护理,比较两组患者认知功能。结果:观察组护理总有效率为93.85%,显著高于对照组72.31%,两组比较差异均有统计学意义(P<0.05)。观察组阳性症状、阴性症状以及一般精神病理评分均低于对照组,观察组总分(51.1±8.9)分低于对照组的(56.2±8.5)分,两组比较差异均有统计学意义(P<0.05)。观察组持续错误数、随机错误数以及正确数评分均低于对照组,观察组总分(70.2±16.7)分,低于对照组的(84.2±17.9)分,两组比较差异均有统计学意义(P<0.05)。结论:在药物治疗的基础上采用综合性心理行为干预,能够更加显著改善患者的认知功能,值得临床推荐。 | 苏美荣 | 2014 | 中外医学研究2014，12，24： | 10 |
| 4 | 精神分裂症患者的情绪调节显示文摘日常生活中,个体通常有不同的理想与目标,当个体被特定的目标驱动,试图去影响自身将要体验到的情绪类别、将要体验到的情绪感受发生的时间,以及如何体验、表达此种情绪时,情绪调节就发生了。精神分裂症是一种复杂的精神疾病,该类疾病患者普遍存在情绪方面的缺陷,通过操控各种内外因素,可以帮助精神分裂症患者进行有效的情绪调节,有利于帮助他们构建健全的情绪体验,对促进其身心健康发展具有现实临床意义。 | 朱传林 李萍 罗文波 齐正阳 何蔚祺 | 2016 | 心理科学进展2016，24，4： | 10 |
| 5 | Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia显示文摘Schizophrenia is hypothesized to arise from disrupted brain connectivity. This 'dysconnectivity hypothesis' has generated interest in discovering whether there is anatomical and functional dysconnectivity between the prefrontal cortex(PFC) and other brain regions, and how this dysconnectivity is linked to the impaired cognitive functions and aberrant behaviors of schizophrenia. Critical advances in neuroimaging technologies, including diffusion tensor imaging(DTI) and functional magnetic resonance imaging(f MRI), make it possible to explore these issues. DTI affords the possibility to explore anatomical connectivity in the human brain in vivo and f MRI can be used to make inferences about functional connections between brain regions. In this review, we present major advances in the understanding of PFC anatomical and functional dysconnectivity and their implications in schizophrenia. We then briefl y discuss future prospects that need to be explored in order to move beyond simple mapping of connectivity changes to elucidate the neuronal mechanisms underlying schizophrenia. | Yuan Zhou Lingzhong Fan Chenxiang Qiu Tianzi Jiang | 2015 | Neuroscience Bulletin2015，31，2： | 9 |
| 6 | 精神分裂症患者暴力行为相关情绪调控障碍及其脑电生理机制显示文摘精神分裂症患者暴力行为对社会造成严重不良影响,为制定预防措施,需找到相关生物学指标。近年的研究开始关注情绪调控障碍在精神分裂症暴力行为中的作用,脑电生理科学的进展使得该类研究有了新的进展。现就精神分裂症暴力行为与情绪调控障碍及其脑电生理研究进展进行综述。 | 李欣 王继军 谢斌 | 2015 | 精神医学杂志2015，28，3： | 7 |
| 7 | 针刺心包经穴位对健康人脑静息态扣带后回功能连接的影响显示文摘目的运用静息态功能性磁共振成像(fMRI)技术探讨针刺心包经(经穴)调控情绪、记忆认知网络的中枢机制。方法对14名健康人进行fMRI扫描。包括:第1次纯静息态扫描(Rest1,R1)、针刺该经脉全经腧穴后扫描(Acupuncture,AP)和第2次静息态扫描(Rest2,R2),应用REST软件取扣带后回(PCC)为种子点进行功能连接分析。结果 R1、R2状态下未出现,仅AP状态下出现的与PCC功能连接显著增强的脑区为双侧颞中回、颞下回,显著减弱的脑区为左侧额中回、额下回,右侧小脑后叶;R1、AP状态下未出现,仅R2状态下出现的与PCC功能连接显著减弱的脑区为右侧小脑后叶、小脑坡部、小脑蚓垂部、额下回。结论针刺心包经经穴后前额叶皮层、小脑与PCC的功能连接活动被抑制,PCC与颞叶皮层的功能连接活动同步增强,通过上述高级认知功能的脑区内部调节,记忆和情绪调控得以实现,该变化可能是心包经经穴治疗具有记忆和情绪认知功能障碍可能的效应机制。 | 韩红艳 张驰 闫镔 童莉 雷煜 周浩 何琦 | 2014 | 北京中医药大学学报2014，37，3： | 6 |
| 8 | Awareness is essential for differential delay eyeblink conditioning with soft-tone but not loud-tone conditioned stimuli显示文摘The role of awareness in differential delay eyeblink conditioning(DEC) remains controversial. Here, we investigated the involvement of awareness in differential DEC with a soft or a loud tone as the conditioned stimulus(CS). In the experiment, 36 participants were trained in differential DEC with a soft tone(60 dB) or a loud tone(85 dB) as the CS, paired with a corneal air-puff as the unconditioned stimulus(US). After conditioning, awareness of the relationship between the CS and the US was assessed with a 17-item true/false questionnaire. Interestingly, during differential DEC with a soft-tone CS, a higher proportion of differential conditioned responses(CRs) was evident in participants who were aware than those who were unaware. In contrast, when a loud tone was used as the CS, the proportion of differential CRs of the aware participants did not differ significantly from those who were unaware over any of the blocks of 20 trials. In unaware participants, the percentage of differential CRs with a loud-tone CS was significantly higher than that with a soft-tone CS; however in participants classified as aware, the percentage of differential CRs with a loud-tone CS did not differ significantly from that with a soft-tone CS. The present findings suggest that awareness is critical for differential DEC when the delay task is rendered more difficult. | He Huang Bing Wu Qiong Li Juan Yao Xuan Li Yi Yang Guang-Yan Wu Jian-Feng Sui | 2014 | Neuroscience Bulletin2014，30，3： | 1 |
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