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| 1 | Neuroprotective effects of salidroside on focal cerebral ischemia/reperfusion injury involve the nuclear erythroid 2-related factor 2 pathway显示文摘Salidroside,the main active ingredient extracted from Rhodiola crenulata,has been shown to be neuroprotective in ischemic cerebral injury,but the underlying mechanism for this neuroprotection is poorly understood.In the current study,the neuroprotective effect of salidroside on cerebral ischemia-induced oxidative stress and the role of the nuclear factor erythroid 2-related factor 2(Nrf2)pathway was investigated in a rat model of middle cerebral artery occlusion.Salidroside(30 mg/kg)reduced infarct size,improved neurological function and histological changes,increased activity of superoxide dismutase and glutathione-S-transferase,and reduced malon-dialdehyde levels after cerebral ischemia and reperfusion.Furthermore,salidroside apparently increased Nrf2 and heme oxygenase-1 expression.These results suggest that salidroside exerts its neuroprotective effect against cerebral ischemia through anti-oxidant mechanisms and that activation of the Nrf2 pathway is involved.The Nrf2/antioxidant response element pathway may become a new therapeutic target for the treatment of ischemic stroke. | Jing Han Qing Xiao Yan-hua Lin Zhen-zhu Zheng Zhao-dong He Juan Hu Li-dian Chen | 2015 | Neural Regeneration Research2015，10，12： | 23 |
| 2 | 红景天在皮肤科的应用研究概况显示文摘近年来,对中药红景天的应用和研究不断拓展深入,红景天相关药物和保健产品的研发也成为热点。因其有较好的抗辐射、抗光老化、美白祛斑等功效,在皮肤科领域的应用和研究也取得一定突破。本文将近年来红景天在皮肤科的应用和研究进展综述如下。1红景天的应用概况红景天(Rhodiola)是景天科红景天属多年生草本或亚灌木植物,在中华医药文献中很早就有记载, | 刘朝圣 刁庆春 | 2017 | 湖南中医杂志2017，33，3： | 4 |
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