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		题名	作者	年代	出处	被引量
	1	Label-free high-throughput and real-time detections of protein interactions by oblique-incidence reflectivity difference method显示文摘Selected Mouse IgG of 1 mg/mL as target was fabricated on microarray for 500 sample dots.Label-free and real-time reaction dynamic processes were detected between the microarrays with Goat Anti-mouse IgG of 0.02 mg/mL using the obliqueincidence reflectivity difference(OIRD)method.We obtained the reaction results and the reaction dynamic curves of 500 protein dots.In addition,we also used label-free detection of protein microarrays of 10080 sample dots,including BSA and different concentrations of Mouse IgG and Rabbit IgG,by OIRD.The obtained reaction results between the protein microarray with 1 mg/mL Goat Anti-mouse IgG and 1 mg/mL Goat Anti-rabbit IgG are reported herein.Experimental results show that OIRD can be not only label-free high-throughput detection method for biological microarrays but also label-free real-time detection in the interaction processes of biomolecules.	HE LiPing LIU Shuang DAI JunBeijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Lü HuiBin JIN KuiJuan YANG GuoZhen	2014	Science China(Physics,Mechanics & Astronomy)2014，57，4：	1
	2	Parallel detection and quantitative analysis of specific binding of proteins by oblique-incidence reflectivity difference technique in label-free format显示文摘In this work,we parallelly detected the specific binding between microarray targets including 12 different kinds of proteins and the probe solution containing five corresponding antibodies and quantitatively analyzed the interactions between CDH13 and solution phase anti-CDH13 at six different probe concentrations by oblique-incidence reflectivity difference(OIRD)method in label-free format.The detection sensitivity reached 10 ng/mL.The experimental results indicate that the OIRD method is a promising and competing technique not only in research work but also in clinic.	DAI Jun LI Lin HE LiPing RUAN KangCheng LU HuiBin JIN KuiJuan YANG GuoZhen	2014	Science China(Physics,Mechanics & Astronomy)2014，57，11：	0

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