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| 1 | 中国胶囊内镜临床应用指南显示文摘中华医学会消化内镜学分会胶囊内镜与小肠镜学组于2008年制订了《中华消化内镜学会胶囊内镜临床应用规范》,对我国规范使用胶囊内镜提供了有力参考。胶囊内镜检查经历10余年的发展,已经成为重要的消化道疾病检查手段,尤其是对小肠疾病的诊断。随着科学技术的不断进步,除了小肠胶囊内镜出现了部分改进之外,专用食管胶囊内镜、专用结肠胶囊内镜和专用磁控胶囊胃镜亦已进入临床应用阶段。 | 戈之铮 李兆申 | 2014 | 中国实用内科杂志2014，34，10： | 35 |
| 2 | 中国胶囊内镜临床应用指南显示文摘中华医学会消化内镜学分会胶囊内镜和小肠镜学组于2008年制订了《中华消化内镜学会胶囊内镜临床应用规范》,对我国规范使用胶囊内镜提供了有力参考。胶囊内镜检查历经10余年的发展,已经成为重要的消化道疾病检查手段,尤其是对小肠疾病的诊断。随着科学技术的不断进步,除小肠胶囊内镜出现部分改进外,食管专用胶囊内镜、结肠专用胶囊内镜以及专用磁控胶囊胃镜亦已进入临床应用阶段。因此。 | | 2014 | 胃肠病学2014，19，10： | 22 |
| 3 | Oral purgative and simethicone before small bowel capsule endoscopy显示文摘AIM:To evaluate small bowel cleansing quality,diagnostic yield and transit time,comparing three cleansing protocols prior to capsule endoscopy.METHODS:Sixty patients were prospectively enrolled and randomized to one of the following cleansing protocols:patients in Group A underwent a 24 h liquid diet and overnight fasting;patients in Group B followed protocol A and subsequently were administered 2 L of polyethylene glycol(PEG) the evening before the procedure;patients in Group C followed protocol B and were additionally administered 100 mg of simethicone 30 min prior to capsule ingestion.Small bowel cleansing was independently assessed by two experienced endoscopists and classified as poor,fair,good or excellent according to the proportion of small bowel mucosa under perfect conditions for visualization.When there was no agreement between the two endoscopists,the images were reviewed and discussed until a consensus was reached.The preparation was considered acceptable if > 50% or adequate if > 75% of the mucosa was in perfect cleansing condition.The amount of bubbles was assessed independently and it was considered significant if it prevented a correct interpretation of the images.Positive endoscopic findings,gastric emptying time(GET) and small bowel transit time(SBTT) were recorded for each examination.RESULTS:There was a trend favoring Group B in achieving an acceptable(including fair,good or excellent) level of cleansing(Group A:65%;Group B:83.3%;Group C:68.4%) [P = not significant(NS)] and favoring Group C in attaining an excellent level of cleansing(Group A:10%;Group B:16.7%;Group C:21.1%)(P = NS).The number of patients with an adequate cleansing of the small bowel,corresponding to an excellent or good classification,was 5(25%) in Group A,5(27.8%) in Group B and 4(21.1%) in Group C(P = 0.892).Conversely,7 patients(35%) in Group A,3 patients(16.7%) in Group B and 6 patients(31.6%) in Group C were considered to have poor small bowel cleansing(P = 0.417),with significant fluid or debris such that the examination was unreliable.The proportion of patients with a significant amount of bubbles was 50% in Group A,27.8% in Group B and 15.8% in Group C(P = 0.065).This was significantly lower in Group C when compared to Group A(P = 0.026).The mean GET was 27.8 min for Group A,27.2 min for Group B and 40.7 min for Group C(P = 0.381).The mean SBTT was 256.4 min for Group A,256.1 min for Group B and 258.1 min for Group C(P = 0.998).Regarding to the rate of complete examinations,the capsule reached the cecum in 20 patients(100%) in Group A,16 patients(88.9%) in Group B and 17 patients(89.5%) in Group C(P = 0.312).A definite diagnosis based on relevant small bowel endoscopic lesions was established in 60% of the patients in Group A(12 patients),44.4% in Group B(8 patients) and 57.8% in Group C(11 patients)(P = 0.587).CONCLUSION:Preparation with 2 L of PEG before small bowel capsule endoscopy(SBCE) may improve small bowel cleansing and the quality of visualization.Simethicone may further reduce intraluminal bubbles.No significant differences were found regarding GET,SBTT and the proportion of complete exploration or diagnostic yield among the three different cleansing protocols. | Bruno Joel Ferreira Rosa Mara Barbosa Joana Magalhes Ana Rebelo Maria Joo Moreira José Cotter | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，2： | 21 |
| 4 | 两种不同时间口服聚乙二醇对小肠胶囊内镜肠道准备效果影响的多中心随机对照研究显示文摘目的比较小肠胶囊内镜(small bowel capsule endoscopy,SBCE)检查前4 h和6 h开始口服2 L聚乙二醇溶液(polyethylene glycol,PEG)的肠道准备效果,探索SBCE肠道准备的合理时间。方法基于3家医院开展多中心随机对照试验,通过计算机随机数字表法按1∶1比例进行中心内随机分组(4 h组、6 h组),按纳入及排除标准,从2016年1月至2018年6月共纳入160例患者,4 h组、6 h组分别于SBCE检查前4、6 h开始口服2 L PEG清肠。主要评价指标为小肠图像质量优秀率,次要指标包括小肠病变诊断率、全小肠完成率、胃通过时间、小肠通过时间。结果 4 h组的小肠图像质量优秀率高于6 h组[(65. 8±17. 4)%vs (59. 3±17. 3)%,P=0. 034]; 4 h组的小肠通过时间短于6 h组[(269. 1±115. 3) vs (313. 9±104. 7) min,P=0. 019]; 4 h组小肠病变诊断率、全小肠完成率、胃通过时间分别为70. 1%(54/77)、86. 7%(66/77)、38. 0(19. 0,89. 5) min,6 h组分别为68. 4%(54/79)、89. 9%(71/79)、28. 5(11. 7,50. 5) min,组间差异无统计学意义(P> 0. 05)。结论两种肠道准备时间方案对诊断率、全小肠完成率、胃通过时间无明显影响,但4 h方案具有更佳的小肠图像质量。 | 杨强强 邓涛 徐红 彭学 杨雪丽 金国花 赵晓晏 | 2018 | 第三军医大学学报2018，40，21： | 10 |
| 5 | 胶囊内镜肠道准备方案的现况和进展显示文摘胶囊内镜(capsule endoscopy)的问世突破了以往小肠检查的盲区,是消化内镜技术领域又一重大里程碑。胶囊内镜不需要像传统胃肠镜一样进行插管,也不需麻醉,具有无痛苦、无交叉感染、安全高效等优势,目前临床应用较为广泛。 | 朱曙光 廖专 李兆申 | 2017 | 中华消化内镜杂志2017，34，7： | 9 |
| 6 | 小肠胶囊内镜在克罗恩病诊断和治疗中的应用进展显示文摘克罗恩病(CD)具有跳跃性、透壁性全消化道炎症的特点。目前内镜、CT肠道造影(CTE)、磁共振肠道造影(MRE)是辅助CD诊断的一线检查手段,但由于小肠特殊的解剖结构,使传统内镜检查受限。MRE、CTE仅对肠壁炎症较敏感,而对小肠黏膜面炎症不敏感,导致小肠CD不易获得早期诊断和治疗。小肠胶囊内镜(SBCE)的问世解决了这一问题。本文就SBCE在CD诊断和治疗中的应用进展作一综述。 | 徐双双 王承党 | 2019 | 胃肠病学2019，24，10： | 3 |
| 7 | OMOM智能胶囊内镜系统临床应用111例分析显示文摘目的探讨OMOM智能胶囊内镜系统(OMOM胶囊内镜)对小肠疾病的诊断价值。方法总结分析我院不明原因消化道出血(OGIB)及慢性腹痛、腹胀、腹泻等患者共111例,所有患者进行胶囊内镜检查前均行胃镜、肠镜及腹部CT检查,未发现可解释疾病的病因。分析胶囊内镜胃内运行时间、小肠运行时间及胶囊内镜对各类症状组检出疾病的检出率、诊断符合率。结果 111例患者检查过程中无明显不适及并发症,全小肠检查成功率96.4%(107/111),胶囊内镜在胃内运行时间平均为(41±18)min,在小肠内运行时间平均为(292±88)min。总病变检出率为82.9%(92/111),诊断符合率为50.5%(56/111),其中OGIB组病变检出率95.5%(42/44),诊断符合率为68.2%(30/44),慢性腹痛组病变检出率为78.3%(36/46),诊断符合率为39.1%(18/46),慢性腹胀组病变检出率为81.8%(9/11),诊断符合率为27.3%(3/11),慢性腹泻病组变检出率为50%(5/10),诊断符合率为20%(2/10)。OGIB组病变检出率和诊断符合率明显高于其他3组(P<0.05)。结论国产OMOM胶囊内镜对小肠疾病诊断率高、安全、无创伤。可作为小肠疾病的常规检查手段,尤其是OGIB的诊断。 | 梅玫 罗雁 刘会领 陆伟 | 2016 | 实用医技杂志2016，23，6： | 2 |
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