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| 1 | Primary liver transplantation vs liver resection followed by transplantation for transplantable hepatocellular carcinoma:Liver functional quality and tumor characteristics matter显示文摘Liver resection(LR) and primary liver transplantation(LT) are two potentially curative treatment modalities for patients with hepatocellular carcinoma(HCC).If an underlying chronic liver disease exists,however,making a decision on which method should be selected is difficult.If a patient has no chronic liver disease,LR may be the preferable option with salvage transplantation(ST) in mind in case of recurrence.Presence of a moderate-to-severe liver failure accompanying HCC usually warrants primary LT.The treatment of patients with HCC and early-stage chronic liver disease remains controversial.The advantages of 'LR-followed-by-STif-needed' strategy include less complicated index operation,no need for immunosuppression,use of donor livers for other patients in today's organ shortage setting and comparable survival rates.However,primary LT has its own advantages as it also treats underlying chronic liver disease with carcinogenic potential,removes undetected tumor nodules and potentially eliminates need for a ST.An article recently published by Fuks et al in Hepatology offers an approach by which selecting between LR-followed-by-ST and immediate LT might be easier.Here we discuss the results of the aforementioned report in the light of currently available knowledge. | Mehmet Fatih Can Christopher B Hughes | 2013 | World Journal of Gastrointestinal Surgery2013，5，1： | 6 |
| 2 | 肝癌肝移植纳入标准研究现状及展望显示文摘肝癌是目前全球范围内最常见的恶性肿瘤之一,其死亡率居所有恶性肿瘤第4位,即使乙肝疫苗的广泛使用,在全球范围内,肝癌的形式仍不容乐观,每年有超过70万新发病例心。肝移植、肝切除及射频消融是被公认对肝癌唯一有效的三种外科治疗手段。由于肝癌的发生大多数都伴有肝硬变,而肝移植能同时移除肿瘤以及肿瘤的“土壤”而被公认为是治疗肝癌的最佳治疗手段。 | 严律南 雷建勇 | 2014 | 中国普外基础与临床杂志2014，21，4： | 4 |
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