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		题名	作者	年代	出处	被引量
	1	AP-2α、Bcl-2及C-myc在重度子痫前期患者胎盘组织中的表达及意义显示文摘目的:探讨转录因子激活蛋白-2α( AP-2α)与B淋巴细胞瘤-2基因( Bcl-2)、C-myc在重度子痫前期胎盘组织中的表达及其意义。方法采用免疫组化法及实时荧光定量-PCR( RT-PCR)的方法,检测重度子痫前期组胎盘组织及正常对照组胎盘组织中AP-2α及Bcl-2、C-myc蛋白及mRNA的表达。结果重度子痫前期组胎盘组织中AP-2α蛋白明显高于正常对照组(P﹤0.05),Bcl-2和C-myc蛋白表达明显低于正常对照组(P﹤0.05);重度子痫前期组胎盘组织中AP-2α mRNA明显高于正常对照组(P﹤0.05),C-myc和Bcl-2 mRNA表达明显低于正常对照组( P﹤0.05)。结论 AP-2α和Bcl-2、C-myc在重度子痫前期患者胎盘组织中的差异表达参与重度子痫前期的病理生理过程。	张玲曾宪旭张展常爱民	2016	中国实用医刊2016，43，16：	1
	2	Assessment of urinary concentration of cotinine in Chinese pregnant women exposed to environmental tobacco smoke显示文摘Environmental tobacco smoke(ETS)is a wellknown reason of many adverse health consequences in pregnant women.Exposure of ETS during pregnancy may increase the risk of some fetal diseases in pregnant women and/or birth defects in neonates.Many countries have implemented laws to control smoking and free of second hand smoke in all enclosed workplaces.In China,antismoking law was enforced in March 2010.We aimed to assess the exposure of pregnant women to cotinine after anti-smoking law was implemented in China.The urine samples were collected from 2,100 volunteers from Zhejiang Province,China and urinary concentration of cotinine was measured using gas chromatography and mass spectrometry.Cotinine was detected in 87%of the pregnant women.The GM and 95th percentile concentration inpregnant women were 4.28 and 44.00 lg/L,respectively.Similarly,the GM and 95th concentration of cotinine were significantly higher in smoking group than in non-smoking group(P\0.0001).Our results indicate that pregnant women in China are at the high risk of exposure ETS.Further attempts are required to make strategies to find out the sources of ETS exposure and prevent smoking at public places especially during pregnancy.	Yajing Lei Wenhui Liu Lizheng Fang Muhammad Sajid Hamid Akash Kanwal Rehman Hua Narenmandura Weixing Shi Weixian Lu Yingchun Xu Shuqing Chen	2014	Chinese Science Bulletin2014，59，13：	0

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