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| 1 | 随机对照临床试验中盲法质量评价现状显示文摘正确使用盲法可以有效控制和减少临床试验过程中由于试验参与人员主观因素所引入的偏倚,但盲法失败时反而会引入更大偏倚。因此,对涉及盲法的临床试验,有必要对其进行盲法质量评价。笔者对目前国际上盲法质量评价的相关文献和方法进行了梳理总结,发现目前盲法质量评价尚未引起研究者的足够重视,相关研究报道较少;更缺乏全面综合的盲法评价方法和工具,对盲法评价时点也无统一意见。因此,有必要对盲法评价方法进行多方面的深入研究,并建议根据影响盲法实施的关键因素开发综合的盲法评价量表,通过评估各关键因素的执行情况,确定研究的盲法风险和等级,便于更好地解释和评估研究结果。 | 闫世艳 何丽云 刘保延 | 2014 | 中国循证医学杂志2014,14,5: | 26 |
| 2 | Efficacy of acupuncture on fibromyalgia syndrome:a Meta-analysis显示文摘OBJECTIVE:To comprehensively evaluate the effectiveness of acupuncture as a treatment for fibromyalgiasyndrome.METHODS: Two review authors independently selected the trials for the Meta-analysis, assessed their methodological quality and extracted relevant data. A quality assessment was conducted according to the Cochrane Review Handbook 5.0.RevMan 5.0.20 software was used in the statistical analysis.RESULTS: A total of 523 trials were reviewed and 9trials were selected for Meta-analysis.(a) Compared acupuncture with sham acupuncture, there was a significant difference in the visual analogue scale,but no difference in the pressure pain threshold.Additionally,and there was a difference in the fibromyalgia impact questionnaire and the multidisciplinary pain inventory after 4 weeks of treatment,but no difference after 7 weeks of therapy. There was no difference in the numerical rating scale in weeks 3, 8 and 13.(b) Acupuncture versus drugs.There were differences in the VAS after 20 days of acupuncture and moxibustion treatment comparing with the drug amitriptyline, and after 4 weeks of acupuncture and moxibustion treatment comparing with the drug fluoxetine and amitriptyline.There were also differences in the number of tender points when comparing acupuncture with amitriptyline or fluoxetine. There was no difference in total efficiency when comparing acupuncture with amitriptyline after 4 weeks of treatment, but there were differences between the two groups 45 days after treatment.There were also differences in total efficiency comparing acupuncture with fluoxetine,and when comparing 4 weeks post-treatment of acupuncture with a combination of amitriptyline,oryzanol and vitamin B.(c) A comparison of acupuncture, drugs and exercise with drugs and exercise showed PPT differences in months 3 and 6.There was no difference between the two comparison groups after follow-up visits in months 12 and 24.CONCLUSION: Compared with sham acupuncture,there was not enough evidence to prove the efficacy of acupuncture therapy for the treatment of fibromyalgia. Some evidence testified that the effectiveness of acupuncture therapy for fibromyalgia was superior to drugs; however, the included trials were not of high quality or had high bias risks.Acupuncture combined with drugs and exercise could increase pain thresholds in the short term, but there is a need for higher quality randomized controlled trials to further confirm this. | Yang Bai Yi Guo Hong Wang Bo Chen Zhankui Wang Yangyang Liu Xue Zhao Yinhong Li | 2014 | Journal of Traditional Chinese Medicine2014,34,4: | 6 |
| 3 | Acupuncture:A Paradigm of Worldwide Cross-Cultural Communication显示文摘On 16 November 2010,an exciting news inspired all traditional Chinese medicine(TCM) practitioners, especially acupuncturists in China.Acupuncture and moxibustion of TCM along with Peking Opera were both inscribed on the Representative List of the Intangible Cultural Heritage of Humanity during the 5th session of the United Nations Educational, Scientific and Cultural Organization(UNESCO) Intergovernmental Committee for the Safeguarding of the Intangible Cultural Heritage meeting in Nairobi. | 徐浩 陈可冀 | 2011 | Chinese Journal of Integrative Medicine2011,17,2: | 3 |
| 4 | 国内男性泌尿生殖系统结核文献中随机对照试验的质量评价显示文摘目的评价国内男性泌尿生殖系统结核文献中随机对照试验(RCT)的方法学质量。方法检索截至2015年8月收录于中国生物医学文献数据库(CBM)、万方、CNKI、维普以及Pub Med中的关于国内男性泌尿生殖系统结核的文献,纳入所有随机对照试验文献,依据CONSORT 2010声明对文献质量进行评价,由两名研究者独立进行文献质量评价。结果共纳入9篇中文文献。质量评价结果显示,大多数文献与CONSORT 2010声明符合率不高。纳入文献对样本量确定、随机序列产生、分配隐藏、盲法、意向性治疗分析等条目的报道不详尽或未见报告,同时在试验局限性、可推广性、试验解释以及其他信息(试验注册、试验方案以及资助)等条目的报告上也不够重视。结论国内男性泌尿生殖系统结核文献中RCT的报告质量较低,与CONSORT 2010声明符合率不高,建议RCT的报告尽量采用CONSORT 2010声明来规范,以提高临床随机对照研究的质量。 | 黄明伟 熊国兵 邱明星 | 2016 | 实用医院临床杂志2016,13,3: | 0 |
| 5 | Assessing the Success of Masking in Acupuncture Trials:Further Insight显示文摘Editor:Hopton and MacPherson are correct in noting that attempts at masking are not always successful,hence unsubstantiated claims of masking are not convincing,hence guidance to cease assessing the success of masking should not be embraced.I take exception,however,to the authors calling this last point 'controversial'.I will concede that it is,in fact,controversial in the sense that tobacco was controversial at a time when certain medical groups still endorsed tobacco,or that the need for surgeons to wash their hands after procedures was controversial at a time when some surgeons simply did not wish to do this.In each case we have controversy arising from the pitting of valid, | Vance W.Berger | 2011 | Chinese Journal of Integrative Medicine2011,17,7: | 0 |