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| 1 | Optimizing the Duration of Dual Antiplatelet Therapy After Implantation of Drug-eluting Coronary Stents显示文摘Percutaneous coronary intervention (PCI) with implantation of drug-eluting stents (DESs) has become the standard of care for coronary artery disease and gives a great impetus to device industry. In 2013, approximately half million patients with coronary artery disease underwent PCI in China with a penetration rate of DES reaching beyond 95%.131 The use of DES including domestic ones is highly effective in preventing coronary restenosis, but there is a collateral cost to be borne in terms of delayed healing or re-endothelialization of the stented arterial segment and risk of stent thrombosisJ41 Therefore. | Ying Shen Wei-Feng Shen | 2015 | Chinese Medical Journal2015，，6： | 4 |
| 2 | 细胞色素P450基因多态性与抗血小板治疗显示文摘 | 沈卫峰 | 2010 | 国际心血管病杂志2010，37，6： | 1 |
| 3 | Domestic coronary drug-eluting stents on a new horizon显示文摘Supported by growing evidence from randomized clinical trials and observational or registry studies,percutaneous coronary intervention (PCI) with implantation of drug-eluting stents (DES) has become the standard of care for coronary artery disease,because of reduced repeat intervention and improved clinical outcomes in comparison with bare metal stent.1-3Currently,majority of coronary artery disease patients with complicated lesion subsets or clinical conditions can be successfully treated with DES-based PCI with favorable results.4-6 In 2011,around 300000 PCI procedures have been performed in China,with the penetration rate of DES reaching beyond 90% in most of the centers. | SHEN Wei-feng | 2012 | Chinese Medical Journal2012，，6： | 1 |
| 4 | 极晚期支架内血栓形成原因及处理显示文摘目的探讨极晚期支架内血栓(LVST)形成原因及处理。方法回顾性分析2005年6月~2010年6月植入雷帕霉素药物洗脱支架(DES)治疗冠状动脉狭窄1548例(共植入2642枚支架)中发生LVST病例的发病和处理的具体情况。结果 1548例中发生2例LVST,LVST发生率为0.13%,1例LVST发生在支架术后41个月(三年半),另1例LVST发生在支架术后26个月(二年两个月)。两例均为停止用双联抗血小板治疗后发生支架内血栓。经过充分的抗栓治疗同时行球囊扩张治疗,血栓影消失,无残余狭窄,未再植入支架。随访75个月,病人无不适症状。结论 LVST形成原因复杂,与停用双抗有关。充分的抗栓同时行球囊扩张治疗是有效的方法。 | 刘睿方 徐方兴 周玉杰 刘同库 徐丽华 | 2017 | 中西医结合心血管病电子杂志2017，5，1： | 0 |
| 5 | 紫杉醇对大鼠血管平滑肌细胞G_1-S检查点作用的研究显示文摘目的:探讨紫杉醇对大鼠血管平滑肌细胞(VSMC)和血管内皮细胞(VEC)G1-S检查点的作用。方法:将大鼠VSMC与VEC进行原代培养,50 nmol/L紫杉醇干预72 h后进行免疫荧光染色和蛋白印迹法检测。结果:同VEC相比,紫杉醇干预的VSMC中BrdU表达明显增加(均P<0.05)。紫杉醇干预的VSMC中cyclin D1、P27表达高于VEC,P21表达较低(均P<0.05)。结论:紫杉醇干预的VSMC同VEC相比,在增殖率与细胞周期调节因子表达方面具有明显差异,紫杉醇对VSMC G1-S检查点有特异性调节作用。 | 静亮 彭希 谢敏杰 喻志源 吕家高 王伟 | 2014 | 内科急危重症杂志2014，20，3： | 0 |
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