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| 1 | 缺血性脑卒中患者患手主动运动及被动运动时的功能性磁共振研究显示文摘目的观察缺血性脑卒中患者患手执行主动及被动运动时的脑激活模式,探讨主动运动和被动运动治疗脑卒中后手功能障碍的中枢机制。方法对5例左侧大脑皮质下脑卒中患者患手执行主动及被动抓握.释放动作,执行动作期间采用血氧水平依赖性功能性磁共振(BOLD-fMRI)进行脑扫描,利用SPM5软件对上述患者试验数据进行分析,使用XJVIEWtoolbox8.11版软件得出人选患者在上述两种运动状态下的脑激活区分布图,并对其在不同运动状态下的脑激活模式特点进行分析比较。结果入选患者患手在执行主动运动时其脑激活部位主要位于对侧感觉运动区(SMC)、运动前区(PMC)、双侧小脑及双侧辅助运动区(SMA),另外同侧SMC及PMC区也有轻度激活;激活脑区主要位于对侧大脑及小脑半球。患手执行被动运动时的脑激活部位主要位于双侧SMC、PMC区、双侧小脑、SMA区;激活脑区平均分布于两侧大脑及小脑半球。与患手主动运动比较,患手被动运动时的脑区激活范围较广泛,激活强度也较高。结论患手执行主动运动和被动运动均可激活脑卒中患者运动相关脑区,提示对脑卒中患者进行主动运动及被动运动均可促进其脑功能重组。 | 蔡伟森 吴毅 吴军发 朱玉连 | 2014 | 中华物理医学与康复杂志2014，36，4： | 13 |
| 2 | Activation of brain areas following ankle dorsiflexion versus plantar flexion Functional magnetic resonance imaging verification显示文摘Changes in activated areas of the brain during ankle active dorsiflexion and ankle active plantar flexion were observed in six healthy subjects using functional magnetic resonance imaging. Excited areas of ankle active dorsiflexion involved the bilateral primary motor area and the primary somatosensory area, as well as the bilateral supplementary sensory area, the primary visual area, the right second visual area, and the vermis of cerebellum. Excited areas of ankle active plantar flexion included the ipsilateral supplementary motor area, the limbic system, and the contralateral corpus striatum. Fine movements of the cerebral cortex control the function of the ankle dorsiflexion to a larger extent than ankle plate flexion, and the function of ankle plate flexion is more controlled by the subcortical area. | Tianyu Jiang Weiping Wu Xinglin Wang Changshui Weng Qiuhua Wang Yanmei Guo | 2012 | Neural Regeneration Research2012，7，7： | 0 |
| 3 | Brain Representation of Active and Passive Hand Movements in Healthy Aged People显示文摘Objective:To reveal the neural network of active and passive hand movements. Method:Seven healthy aged people were checked, and acquired functional magnetic resonance imaging data on a 1.5T scanner. Active movement consisted of repetitive grasping and loosening of hand; passive movement involved the same movement performed by examiner. Both types of hand movements were assessed separately. These data were analysed by Statistical Parametric Mapping Microsoft. Result:The main activated brain areas were the contralateral supplemental motor area, primary motor area, primary sensory area and the ipsilateral cerebellum when subjects gripped right hands actively and passively. The supplemental area was less active in passive hand movement than active hand movement. The activated brain areas were mainly within Brodmann area 4 during active hand movement; in the contrast, the voxels triggered by passive movement were mainly within Brodmann areas 3,1,2 areas. Conclusion:The results suggest that the neural networks of passive and active tasks spared some common areas, and the passive movement could be as effective as active movement to facilitate the recovery of limbs motor function in patients with brain damage. | CAI Weisen WU Yi WU Junfa | 2013 | 中国康复医学杂志2013，28，6： | 0 |
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