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    题名 作者 年代 出处 被引量
1An Appreciation for the Rabbit Ladderlike Modeling of Radiation-induced Lung Injury with High-energy X-Ray显示文摘Xiang-Ming Fang Chun-Hong Hu Xiao-Yun Hu Xuan-Jun Yao Ping-Yan Qian Ju-Ying Zhou Jian Guo Alexander Lerner 2015Chinese Medical Journal2015,,12:8
2CT定量测量成人游离性胸腔积液的归一化方程显示文摘【目的】探讨胸腔积液量与胸腔积液CT横断面上最大深度、矢状面最大纵向累及长度之间的关系,建立多重线性回归模型估算胸腔积液量。【方法】收集151名18岁以上游离性胸腔积液患者的CT检查资料,共166个胸腔积液。测算胸腔积液体积V、胸腔积液CT横断面上最大深度H、矢状面最大纵向累及长度L,随机抽取70%的样本作为训练样本,剩下的为验证样本量。以经对数转换后的胸腔积液体积V为因变量,其余测量指标为自变量,采用多重线性回归方法建立预测模型。【结果】所得线性回归方程为:ln(V)=0.01688H+0.00578L+4.19738,决定系数R2=0.929。由配对设计资料的t检验可得,在验证样本中V测量值与预测值的差值(X=0.203,95%CI(-0.181,0.587),P=0.883)与0没有统计学意义。V测量值与预测值之间的散点图提示两者之间呈高度的线性相关关系(r=0.962,P<0.01)。【结论】在CT图像上,用胸腔积液CT横断面上最大深度H、矢状面最大纵向累及长度L这两个简单、容易测量的指标可以准确地预测胸腔积液量。严超贵 霍梦娟 范淼 王俊丽 杨有优 2016中山大学学报(医学科学版)2016,37,5:3
3Rabbit model of radiation-induced lung injury显示文摘Objective:To explore the feasibility of establishing an animal model of chronic radiationinduced lung injury.Methods:Twenty-eight New Zealand white rabbits were randomly divided into 3 groups(the right lung irradiation group,the whole lung irradiation group and the control group).Animal model of radiation-induced lung injury was established b) highdoes radiotherapy in the irradiation groups,then all rabbits underwent CT and pathological examinations at 1.2.4.8.12.16 weeks,respectively after radiation.Results:Within 4 weeks of irradiation,some rabbits in the right lung irradiation group and whole lung irradiation group died. CT and pathological examinations all showed acute radiation pneumonitis.At 8-12 weeks after irradiation,CT scanning showed ground glass samples signs,patchy shadows and fibrotic stripes. Pathological examination showed the fibrosis pulmonary alveolar wall thickened obviously. Conclusions:The clinical animal model of chronic radiation-induced lung injury which corresponds to practical conditions in clinic can be successfully established.Zhen-Zong Du Hua Ren Jian-Fei Song Li-Fei Zhang Feng Lin Hai-Yong Wang 2013Asian Pacific Journal of Tropical Medicine2013,6,3:2
4放化疗相关性肺损伤的研究进展显示文摘放化疗已成为大部分不能手术切除的局部进展晚期肺癌、食道癌等胸部肿瘤的主要治疗选择。而放化疗引起的治疗相关性肺损伤成为限制治疗效果的主要因素之一,同时也影响了患者的生存质量,甚至危及生命。该文综述了近年来放化疗相关性肺损伤在发病机制、病理改变、影像学表现及诊治方面的研究现状和进展。李功祥 李险峰 2010国际放射医学核医学杂志2010,34,4:2
5Advancements in radiotherapy for lung cancer in China显示文摘Lung cancer is the leading cause of death due to cancer in China. In recent years, great progress has been made in radiotherapy for lung cancer patients in China. The main advancements include the following aspects:(1) stereotactic ablative radiotherapy for early stage nonsmall cell lung cancer(NSCLC),(2) post-operative radiotherapy for NSCLC,(3) combined chemotherapy and radiotherapy for locally advanced NSCLC,(4) improved radiotherapy for advanced NSCLC, and 5) prediction of radiation-induced lung toxicity.Lujun Zhao Luhua Wang 2015The Chinese-German Journal of Clinical Oncology2015,14,1:0
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