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| 1 | Synthesis of novel isoxazolyl bis-thiazolo[3,2-a]pyrimidines显示文摘A new synthetic strategy for the synthesis of novel 3-(3-(3-methyl-4-nitroisoxazol-5-yl)-2-phenyl-1-(5,7-diaryl-7H-thiazolo[3,2-a]pyrimidin-3-yl)propyl)-5,7-diaryl-7H-thiazolo[3,2-a] pyrimidines(7a-i) analogues is described.Reaction of 3-(2(3-methyl-4-nitroisoxazole-5-yl)-1-phenylethyl)pentane-2,4-dione(3) with two moles of thiourea in presence of iodine and CuO afforded 4-(1-(2-aminothiazol-4-yl)-3-(3-methyl-4-nitroisoxazol-5-yl)-2-aryl propyl-thiazol-2-amine(5).Compound 5 on reaction with two moles of chalcone(6) furnished novel 3-(3-(3-methyl-4-nitroisoxazol-5-yl)-2-phenyl-1-(5,7-diaryl-7H-thiazolo[3,2a]pyrimidin-3-yl)propyl)-5,7-diaryl-7H-thiazolo[3,2-a] pyrimidines(7a-i). | E.Rajanarendar S.Ramakrishna K.Rama Murthy | 2012 | Chinese Chemical Letters2012，23，8： | 3 |
| 2 | A facile and convenient synthesis of novel imidazo[1,2-b] isoxazoles and their Mannich bases as potential biodynamic agents显示文摘A series of novel imidazo[1,2-b]isoxazoles 3 and their Mannich bases 4–6 were synthesized via convenient reactions. The reaction of 3-aminoisoxazole 1 with substituted phenacyl bromides 2 in dry ethanol afforded the corresponding 6-methyl-3-aryl imidazo[1,2-b]isoxazoles 3 in good yields.Compounds 3 on treatment with 37% formaline and secondary amines furnished the corresponding novel Mannich bases viz., 6-methyl-3-aryl-2-(morpholine/pyrrolidin-1-yl/piperidin-1-yl)-methyl-imidazo[1,2-b]isoxazoles 4–6. | E.Rajanarendar K.Thirupathaiah S.Ramakrishna D.Nagaraju | 2015 | Chinese Chemical Letters2015，26，12： | 2 |
| 3 | DABCO-promoted facile and convenient synthesis of novel isoxazolyl-1H-2,3-pyrrole dicarboxylates显示文摘Synthesis of isoxazolyl-1H-2,3-pyrrole dicarboxylate(4) was simply achieved by one-pot three component reaction of isoxazole amine(1) with diethyl acetylenedicarboxylate(DEAD)(2),and glyoxal (3),in acetonitrile catalyzed by diazabicyclo octane(DABCO). | Rajanarendar Eligeti Kishore Baireddy Ramakrishna Saini | 2013 | Chinese Chemical Letters2013，24，2： | 2 |
| 4 | A selective and sensitive off–on probe for palladium and its application for living cell imaging显示文摘A new rhodamine B derivative T1 has been rationally synthesized and displayed selective Pd(Ⅱ)-amplified absorbance and fluorescence emission above 540 nm in methanol–water. Upon the addition of Pd(Ⅱ), the spirolactam ring was unfolded and a 1:1 metal-ligand complex formed, which can be used for ‘‘naked-eyes' detection. In addition, fluorescence imaging experiments of Pd^(2+) in HepG2 living cells showed its valuable application in biological systems. | Ying Long Jia Zhou Mei-Pan Yang Bing-Qin Yang | 2016 | Chinese Chemical Letters2016，27，2： | 2 |
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