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| 1 | Video capsule endoscopy:Perspectives of a revolutionary technique显示文摘Video capsule endoscopy(VCE)was launched in 2000and has revolutionized direct endoscopic imaging of the gut.VCE is now a first-line procedure for exploring the small bowel in cases of obscure digestive bleeding and is also indicated in some patients with Crohn’s disease,celiac disease,and polyposis syndrome.A video capsule has also been designed for visualizing the esophagus in order to detect Barrett’s esophagus or esophageal varices.Different capsules are now available and differ with regard to dimensions,image acquisition rate,battery life,field of view,and possible optical enhancements.More recently,the use of VCE has been extended to exploring the colon.Within the last 5 years,tremendous developments have been made toward increasing the capabilities of the colon capsule.Although colon capsule cannot be proposed as a first-line colorectal cancer screening procedure,colon capsule may be used in patients with incomplete colonoscopy or in patients who are unwilling to undergo colonoscopy.In the near future,new technological developments will improve the diagnostic yield of VCE and broaden its therapeutic capabilities. | Simon Bouchard Mostafa Ibrahim Andre Van Gossum | 2014 | World Journal of Gastroenterology2014,20,46: | 12 |
| 2 | Capsule endoscopy:Current practice and future directions显示文摘Capsule endoscopy(CE)has transformed investigation of the small bowel providing a non-invasive,well tolerated means of accurately visualising the distal duodenum,jejunum and ileum.Since the introduction of small bowel CE thirteen years ago a high volume of literature on indications,diagnostic yields and safety profile has been presented.Inclusion in national and international guidelines has placed small bowel capsule endoscopy at the forefront of investigation into suspected diseases of the small bowel.Most commonly,small bowel CE is used in patients with suspected bleeding or to identify evidence of active Crohn’s disease(CD)(in patients with or without a prior history of CD).Typically,CE is undertaken after upper and lower gastrointestinal flexible endoscopy has failed to identify a diagnosis.Small bowel radiology or a patency capsule test should be considered prior to CE in those at high risk of strictures(such as patients known to have CD or presenting with obstructive symptoms)to reduce the risk of capsule retention.CE also has a role in patients with coeliac disease,suspected small bowel tumours and other small bowel disorders.Since the advent of small bowel CE,dedicated oesophageal and colon capsule endoscopes have expanded the fields of application to include the investigation of upper and lower gastrointestinal disorders.Oesophageal CE may be used to diagnose oesophagitis,Barrett’s oesophagus and varices but reliability in identifying gastroduodenal pathology is unknown and it does not have biopsy capability.Colon CE provides an alternative to conventional colonoscopy for symptomatic patients,while a possible role in colorectal cancer screening is a fascinating prospect.Current research is already addressing the possibility of controlling capsule movement and developing capsules which allow tissue sampling and the administration of therapy. | Melissa F Hale Reena Sidhu Mark E McAlindon | 2014 | World Journal of Gastroenterology2014,20,24: | 9 |
| 3 | Capsule endoscopy显示文摘Capsule endoscopy(CE) is a simple,safe,non-invasive,reliable technique,well accepted and tolerated by the patients,which allows complete exploration of the small intestine.The advent of CE in 2000 has dramatically changed the diagnosis and management of many diseases of the small intestine,such as obscure gastrointestinal bleeding,Crohn's disease,small bowel tumors,polyposis syndromes,etc.CE has become the gold standard for the diagnosis of most diseases of the small bowel.Lately this technique has also been used for esophageal and colonic diseases. | Miguel Muoz-Navas | 2009 | World Journal of Gastroenterology2009,15,13: | 8 |
| 4 | Role of capsule endoscopy in inflammatory bowel disease显示文摘Videocapsule endoscopy(VCE) has revolutionized our ability to visualize the small bowel mucosa. This modality is a valuable tool for the diagnosis of obscure small bowel Crohn's disease(CD), and can also be used for monitoring of disease activity in patients with established small-bowel CD, detection of complications such as obscure bleeding and neoplasms, evaluation of response to anti-inflammatory treatment and postoperative recurrence following small bowel resection. VCE could also be an important tool in the management of patients with unclassified inflammatory bowel disease, potentially resulting in reclassification of these patients as having CD. Reports on postoperative monitoring and evaluation of patients with ileal pouch-anal anastomosis who have developed pouchitis have recenty been published. Monitoring of colonic inflammatory activity in patients with ulcerative colitis using the recently developed colonic capsule has also been reported. Capsule endoscopy is associated with an excellent safety profile. Although retention risk is increased in patients with small bowel CD, this risk can be significanty decreased by a routine utilization of a dissolvable patency capsule preceding the ingestion of the diagnostic capsule. This paper contains an overview of the current and future clinical applications of capsule endoscopy in inflammatory bowel disease. | Uri Kopylov Ernest G Seidman | 2014 | World Journal of Gastroenterology2014,20,5: | 4 |
| 5 | 228例胶囊内镜检查的回顾分析显示文摘目的探讨胶囊内镜(CE)在小肠克罗恩病(CD)检查中的应用、临床特点和并发症。方法分析228例CE检查的指征、诊断结果,比较CD与非CD的全小肠检查完成率和胶囊滞留率,完成全小肠检查者的小肠通过时间。结果共诊断CD 29例,占12.7%(29/228),其检查指征为,不明原因腹痛或(和)腹泻而怀疑CD者19例,不明原因消化道出血而怀疑CD者5例,CD治疗后复查5例。其CE表现包括:纵行溃疡(75.9%,22/29)或阿弗他溃疡(24.1%,7/29),节段性分布,假息肉样增生(37.9%,11/29),肠腔狭窄(34.5%,10/29)等。CD组全小肠检查完成率为62.1%(18/29),非CD组为82.4%(164/199),前者低于后者(P=0.023)。CD组的小肠通过时间为(4.35±1.83)h(n=18),非CD组为(4.54±1.86)h(n=164),差异无显著性(P=0.689)。CD组胶囊滞留率为13.8%(4/29),非CD组为1.0%(2/199),前者高于后者(P=0.003)。结论 CD患者CE检查的完成率较低,胶囊滞留的风险较高,检查前应仔细询问病史、体格检查,配合腹部平片、小肠钡餐造影,甚至CT、MRI等检查,排除小肠狭窄、不全肠梗阻等,尽可能避免胶囊滞留。 | 游思洪 彭炤源 熊观瀛 黄光明 | 2014 | 中国内镜杂志2014,20,7: | 4 |