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| 1 | Prognostication and response assessment in liver and pancreatic tumors:The new imaging显示文摘Diffusion-weighted imaging(DWI), dynamic contrastenhanced magnetic resonance imaging(DCE-MRI) and perfusion computed tomography(CT) are technical improvements of morphologic imaging that can evaluate functional properties of hepato-bilio-pancreatic tumors during conventional MRI or CT examinations.Nevertheless, the term 'functional imaging' is commonly used to describe molecular imaging techniques, as positron emission tomography(PET)CT/MRI, which still represent the most widely used methods for the evaluation of functional properties of solid neoplasms; unlike PET or single photon emission computed tomography, functional imaging techniques applied to conventional MRI/CT examinations do not require the administration of radiolabeled drugs or specific equipments. Moreover, DWI and DCE-MRI can be performed during the same session, thus providing a comprehensive 'one-step' morphological and functional evaluation of hepato-bilio-pancreatic tumors. Literature data reveal that functional imaging techniques could be proposed for the evaluation of these tumors before treatment, given that they may improve staging and predict prognosis or clinical outcome. Microscopic changes within neoplastic tissues induced by treatments can be detected and quantified with functional imaging,therefore these techniques could be used also for posttreatment assessment, even at an early stage. The aim of this editorial is to describe possible applications of new functional imaging techniques apart frommolecular imaging to hepatic and pancreatic tumors through a review of up-to-date literature data, with a particular emphasis on pathological correlations,prognostic stratification and post-treatment monitoring. | Riccardo De Robertis Paolo Tinazzi Martini Emanuele Demozzi Gino Puntel Silvia Ortolani Sara Cingarlini Andrea Ruzzenente Alfredo Guglielmi Giampaolo Tortora Claudio Bassi Paolo Pederzoli Mirko D'Onofrio | 2015 | World Journal of Gastroenterology2015，21，22： | 10 |
| 2 | 扩散加权成像及表观扩散系数诊断经导管肝动脉化疗栓塞术后存活或复发肝细胞癌病灶价值的Meta分析显示文摘目的探讨扩散加权成像(DWI)及表观扩散系数(ADC)值诊断经导管肝动脉化疗栓塞(TACE)术后存活或复发肝细胞癌(rHCC)的价值.方法检索PubMed、Embase、Cochrane Library、Web of Science、知网、万方数据库中DWI及ADC值诊断rHCC的研究,检索时间截止至2020年1月.2名研究人员独立进行资料提取、质量评价后,运用Stata 12.0软件合并敏感度(Sen)、特异度(Spe)及曲线下面积(AUC),并采用Revmann 5.3软件比较分析rHCC和坏死HCC病灶的ADC值.结果共纳入15篇DWI及ADC值诊断rHCC的研究,包括767例患者的940处病灶.Meta分析结果提示DWI诊断rHCC的Sen、Spe和AUC分别为87%[95%置信区间(CI)0.78~0.92]、84%(95%CI 0.78~0.89)和0.91%(95%CI 0.88~0.93).rHCC病灶的ADC值明显低于坏死HCC病灶[平均扩散率(MD)=-0.48,95%CI-0.66~-0.29,P<0.01].结论DWI对诊断TACE术后rHCC病灶具有较高的准确性,rHCC病灶的ADC值明显低于坏死HCC病灶,DWI可作为诊断TACE术后随访的有效影像学方法. | 车宽余 刘冰芳 胡海英 黄煜 吕小娟 杨小飞 | 2021 | 实用放射学杂志2021，37，4： | 5 |
| 3 | 肝癌TACE术后肝实质损害的CT表现及临床意义显示文摘目的探讨经导管肝动脉化疗栓塞术(TACE)治疗肝癌后继发肝实质损伤的发生机制及CT表现。方法对146例患者做TACE589次,观察TACE术后肝实质损伤的发生机制及CT表现。结果胆管损伤5例,表现为碘油沉积区边缘低或水样密度影;动静脉瘘7例,病灶周围肝实质呈不规则形或楔形提早强化区;肝实质萎缩27例,表现为胆管损伤区肝叶-段呈进行性萎缩。结论熟悉TACE术引起肝实质损害的机制及CT表现有重要临床意义,对确定治疗效果及识别肿瘤复发或新生病灶有重要参考价值。 | 韦树长 梁海英 | 2011 | 中国误诊学杂志2011，11，33： | 1 |
| 4 | 肿瘤性和非肿瘤性肝动脉-门静脉分流的研究进展显示文摘肝内动脉-门静脉分流(hepatic arterioportal shunt,APS)是指肝内的肝动脉系统和静脉系统之间形成直接的功能性和器质性交通支。肿瘤因素所致的APS称为肿瘤性APS,非肿瘤性因素所致的APS称为非肿瘤性APS。正确地诊断APS不仅对肝癌的诊断有辅助作用,而且在APS治疗方面有着重要的意义, | 孙冬 杜勇 杨汉丰 | 2012 | 中华临床医师杂志(电子版)2012，6，23： | 1 |
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