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    题名 作者 年代 出处 被引量
1BOLD-fMRI和DTI在脑肿瘤中应用进展显示文摘血氧水平依赖功能磁共振成像(blood-oxygen level dependent functional MR imaging,BOLD—fMRI)能够无创伤地对神经元活动进行较准确的定位.在脑机能活动的同时。获得解剖学、生理学及病理学信息;弥散张量成像(diffusion tensor imaging,DTI)是目前惟一能在活体中显示神经纤维束的走行、方向、排列、髓鞘等信息,能够无创地研究脑白质纤维束形态结构的技术.目前这两者越来越多地应用于神经外科的研究。邓国军 李东海 2010江西医药2010,45,2:1
2Identification of the primary motor area by three-dimensional reconstruction of the corticospinal tract using diffusion tensor imaging显示文摘Functional MRI (fMRI) is widely used as a non-invasive method for the evaluation of pre-operation motor function.However,patients with cortical function impairment,such as those with hemiparesis,can rarely achieve hand clenching,a typical fMRI task for central sulcus identification,and the method is also of limited use in uncooperative children.Thus,it is important to develop a new method for identifying primary motor areas (PMA) in such individuals.This study used corticospinal tractography to identify the PMA in 20 patients with deep-seated brain tumor.Two regions of interest were set within the brainstem for corticospinal tract (CST) fiber tracking:one at the level of the pons and the other at the level of the cerebral peduncle.The CST fiber tracking results and fMRI activation signals were merged with three-dimensional anatomic MRI findings.The consistency of identifying the PMA by CST and fMRI was analyzed.fMRI activation signals were distributed mainly in the contralateral central sulcus around the omega-shaped hand knob.The CST consistently propagated from the pons and cerebral peduncle to the suspected PMA location.There was a good correlation between CST fiber tracking results and fMRI activation signals in terms of their abilities to identify the PMA.The differences between fMRI and CST fiber tracking findings may result from our functional task,which consisted only of hand movements.Our results indicate that diffusion tensor imaging is a useful brain mapping technique for identifying the PMA in paralyzed patients and uncooperative children.Guojun Deng Luo Li Guimei Chen Erming Zeng Xiangzuo Xiao Meihua Li Tao Hong Donghai Li 2011Neural Regeneration Research2011,6,14:0
3弥散张量成像定位初级运动功能区的研究显示文摘目的 探讨弥散张量成像在定位初级运动功能区的价值.方法 20例脑深部肿瘤患者,分别进行常规MRI、fMRI及DTI检查,获取fMRI脑激活图、DTI图、3D解剖图.DTI通过三维重建皮质脊髓束定位初级运动功能区.fMRI采用手握拳激发模式,获取激活信号定位初级运动功能区.比较两种技术的吻合度,以评价DTI三维重建皮质脊髓束定位的初级运动功能区的准确性.结果 20例患者fMRI获得的激活信号主要位于对侧中央沟处,围绕着"Ω"形柄状结构分布,中央前回位于激活信号前方.所有患者均成功地完成DTI皮质脊髓束的三维重建,重建的皮质脊髓束也定位于激活信号前的脑回,两者均较好显示初级运动功能区且具有较好的一致性.结论 DTI可较好地定位初级运动功能区,这对于有肢体瘫痪患者及不能合作的儿童的初级运动功能区的定位有重要意义.邓国军 李东海 陈桂美 肖香佐 2010中华神经外科杂志2010,26,11:0
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