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    题名 作者 年代 出处 被引量
1伴有肝转移的结直肠癌患者血清CEA、CA199的分析显示文摘目的探讨血清CEA、CA199在晚期结直肠癌中的分布及与临床特征的关系。方法将275例CRC患者分别按性别、年龄、肝转移、腹水、肠瘤直径、肠瘤位置、血便、乙肝进行分组,总结分析患者血清CEA、CA199的浓度均值、阳性率及与临床特征的关系。结果伴肝转移,肿瘤位于结肠,有血便,有腹水的CRC患者中血清CEA、CA199的浓度均值均明显升高,差异有统计学意义(P<0.05)。而血清CEA、CA199的水平与性别、年龄、肠瘤直径、乙肝无明显相关性(P>0.05)。结论血清CEA、CA199可作为早期诊断结直肠癌肝转移的一种有效方法,广泛的用于临床。惠菲菲 刘凯 范明明 杨家和 2015中华结直肠疾病电子杂志2015,4,4:5
2Avoiding hepatic metastasis naturally: Lessons from the cotton top tamarin(Saguinus oedipus )显示文摘Much has been written about hepatic metastasis and animal models abound. In terms of the human experience, progress in treating this final common pathway, a terminal event of many human malignancies has been relatively slow. The current thinking is that primary prevention is best served by early detection of cancer and eradication of early stage cancers by screening. Some cancers spread early in their course and the role of screening may be limited. Until relatively recently there has not been a pathfinder model that makes the evasion of this unfortunate event a reality. This review discusses such an animal model and attempts to relate it to human disease in terms of intervention. Concrete proposals are also offered on how scientists may be able to intervene to prevent this deadly progression of the cancer process.Martin Tobi Peter Thomas Daniel Ezekwudo 2016World Journal of Gastroenterology2016,22,24:0
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