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| 1 | Management of diabolical diabetes mellitus and periodontitis nexus: Are we doing enough?显示文摘Periodontitis is the commonest oral disease affecting population worldwide.This disease is notorious for the devastation of tooth supporting structures,ensuing in the loss of dentition.The etiology for this disease is bacterial biofilm,which accumulates on the teeth as dental plaque.In addition to the biofilm microorganisms,other factors such as environmental,systemic and genetic are also responsible in progression of periodontitis.Diabetes mellitus(DM) is metabolic disorder which has an impact on the global health.DM plays a crucial role in the pathogenesis of periodontitis.Periodontitis is declared as the 'sixth' major complication of DM.Evidence based literature has depicted an enhanced incidence and severity of periodontitis in subjects with DM.A 'two way' relationship has been purported between periodontitis and DM.Mutual management of both conditions is necessary.Periodontal therapy(PT) may assist to diminish the progression of DM and improve glycemic control.Various advanced technological facilities may be utilized for the purpose of patient education and disease management.The present paper clarifies the etio-pathogenesis of periodontitis,establishing it as a complication of DM and elaborating the various mechanisms involved in the pathogenesis.The role of PT in amelioration of DM and application of digital communication will be discussed.Overall,it is judicious to create an increased patient cognizance of the periodontitis-DM relationship.Conjunctive efforts must be undertaken by the medical and oral health care professionals for the management of periodontitis affected DM patients. | Abhijit N Gurav | 2016 | World Journal of Diabetes2016，7，4： | 22 |
| 2 | 钠-葡萄糖共转运蛋白2抑制剂对糖尿病肾病的保护作用显示文摘钠-葡萄糖共转运蛋白2(sodium-glucose cotransporters-2,SGLT2)抑制剂是一种新型的降糖药物。目前有研究表明SGLT2抑制剂除有效降低血糖外,对糖尿病肾病可能有保护作用,主要表现在减少尿蛋白、降低血尿酸、改善肾脏组织学及形态学的病理学改变等,可能与抗氧化、抗炎、抗纤维化,改善肾脏的高滤过,降血压等机制有关。 | 胡钰梅 夏佳佳 任伟 | 2015 | 重庆医科大学学报2015，40，11： | 1 |
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