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| 1 | Relationship between coronary artery ectasia, cocaine abuse and acute coronary syndromes显示文摘Coronary artery ectasia(CAE)often represents a coronary angiography finding casually detected or following the occurrence of an acute coronary syndrome.The pathogenetic role of cocaine abuse in the genesis of CAE is still little known and very few data are available in literature.We describe a case of a 31-year-old male cocaine user admitted to our department for typical acute chest pain.Coronary angiography showed diffuse coronary ectasia with slow flows and without hemodynamically significant stenosis.An increasing of matrix metalloproteinases values and a reduction of their tissue inhibitors was showed both during hospitalization and at one month after discharge.This case report emphasizes the close relationship between cocaine abuse,CAE and acute coronary syndromes in patients without hemodynamically significant coronary stenosis.As reported by Satran et al,cocaine abuse should be considered an important risk factor for CAE and these patients appear to be at increased risk of angina and acute myocardial infarct.Further studies that can strengthen this hypothesis would be useful to deepen and better analyze this interesting association. | Gregory Dendramis Claudia Paleologo Davide Piraino Pasquale Assennato | 2016 | World Journal of Cardiology2016，8，5： | 0 |
| 2 | 冠状动脉瘤合并严重狭窄介入治疗随访1年显示文摘患者,男,66岁,因持续性胸痛1.5h入院。既往有高血压、糖尿病病史,否认高血脂、吸烟史。入院时查体:血压90/60mm Hg,神志清,口唇无紫绀,颈静脉无怒张。双肺未闻及干湿性啰音。心界不大,心率76次/分,律齐,各瓣膜听诊区未闻及杂音。腹软,无压痛及反跳痛。双下肢无水肿。心电图示窦性心律,V1~3导联病理性Q波、V1~6导联ST段抬高0. | 李琳 李琦 赵培勇 | 2016 | 临床合理用药杂志2016，9，22： | 0 |
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