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1Dyslipidemia management in primary prevention of cardiovascular disease:Current guidelines and strategies显示文摘Cardiovascular disease is the leading cause of death in the United States. In 2010, the Centers for Disease Control and Prevention estimated that $444 billion was spent on cardiovascular diseases alone, about $1 of every $6 spent on health care. As life expectancy continues to increase, this annual cost will also increase, making costeffective primary prevention of cardiovascular disease highly desirable. Because of its role in development of atherosclerosis and clinical events, dyslipidemia management is a high priority in cardiovascular prevention. Multiple major dyslipidemia guidelines have been published around the world recently, four of them by independent organizations in the United States alone. They share the goal of providing clinical guidance on optimal dyslipidemia management, but guidelines differ in their emphasis on pharmacotherapy, stratification of groups, emphasis on lifestyle modification, and use of a fixed target or percentage reduction in low density lipoprotein cholesterol. This review summarizes eight major guidelines for dyslipidemia management and considers the basis for their recommendations. Our primary aim is to enhance understanding of dyslipidemia management guidelines in patient care for primary prevention of future cardiovascular risk.Aditya D Hendrani Tolulope Adesiyun Renato Quispe Steven R Jones Neil J Stone Roger S Blumenthal Seth S Martin 2016World Journal of Cardiology2016,8,2:5
2关注老年人多重心血管疾病危险因素及治疗控制目标显示文摘随着社会的发展,我国老年人口及心血管疾病的患病率日益增长。血压、血糖、血脂为心脑血管事件的独立危险因素。对心房颤动患者,应用华法林抗凝国际标准比率(INR)的调控也对抗栓治疗及用药安全起到至关重要的作用。但是,现有的大部分大型临床试验不纳入老年人,尤其是高龄老人,这使得老年人心血管疾病危险因素的控制目标的制定更为复杂和具有争议。本文将对上述老年人心血管危险因素的控制目标进行讨论。冯若璇 秦明照 2016中华临床医师杂志(电子版)2016,10,13:2
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