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| 1 | 信息化平台医疗健康管理在食管癌术后患者中的应用显示文摘目的探讨信息化平台医疗健康管理对食管癌术后患者实施的效果。方法选取2014年1月至2014年12月符合纳入标准的60例行食管癌手术并出院患者,随机分为干预组(30例)和对照组(30例)。对照组30例在出院后按照传统的健康教育模式进行电话随访,干预组30例在对照组的基础上由科内健康管理小组成员采用电话随访、QQ群、微信群、医院网站等信息化平台进行医疗健康管理。比较干预后1个月、3个月及6个月两组患者健康知识掌握情况、并发症发生率、自我护理能力的差异。结果干预后1个月、3个月及6个月,干预组并发症发生率低于对照组(P<0.05),自我护理能力及健康知识掌握程度均高于对照组(P<0.05)。结论信息化平台医疗健康管理,能有效降低并发症发生率,提高患者健康知识掌握程度及自我护理能力,从而降低了患者再次住院率,提高了患者的生活质量。 | 徐庆 袁佰通 赵荣华 项彩霞 汪红艳 詹必成 刘建 | 2016 | 安徽医学2016，37，5： | 14 |
| 2 | Long-pulse gastric electrical stimulation protects interstitial cells of Cajal in diabetic rats via IGF-1 signaling pathway显示文摘AIM: To investigate the effects of different parameters of gastric electrical stimulation(GES) on interstitial cells of Cajal(ICCs) and changes in the insulin-like growth factor 1(IGF-1) signal pathway in streptozotocininduced diabetic rats.METHODS: Male rats were randomized into control, diabetic(DM), diabetic with sham GES(DM + SGES), diabetic with GES1(5.5 cpm, 100 ms, 4 m A)(DM + GES1), diabetic with GES2(5.5 cpm, 300 ms, 4 m A)(DM + GES2) and diabetic with GES3(5.5 cpm, 550 ms, 2 m A)(DM + GES3) groups. The expression levels of c-kit, M-SCF and IGF-1 receptors were evaluated in the gastric antrum using Western blot analysis. The distribution of ICCs was observed using immunolabeling for c-kit, while smooth muscle cells and IGF-1 receptors were identified using α-SMA and IGF-1R antibodies. Serum level of IGF-1 was tested using enzyme-linked immunosorbent assay. RESULTS: Gastric emptying was delayed in the DM group but improved in all GES groups, especially in the GES2 group. The expression levels of c-kit, M-SCF and IGF-1R were decreased in the DM group but increased in all GES groups. More ICCs(c-kit+) and smooth muscle cells(α-SMA+/IGF-1R+) were observed in all GES groups than in the DM group. The average level of IGF-1 in the DM group was markedly decreased, but it was up-regulated in all GES groups, especially in the GES2 group. CONCLUSION: The results suggest that long-pulse GES promotes the regeneration of ICCs. The IGF-1 signaling pathway might be involved in the mechanism underlying this process, which results in improved gastric emptying. | Hai Li Yan Chen Shi Liu Xiao-Hua Hou | 2016 | World Journal of Gastroenterology2016，22，23： | 5 |
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