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1Enhanced recovery pathways in pancreatic surgery: State of the art显示文摘Pancreatic surgery is being offered to an increasing number of patients every year. Although postoperative outcomes have significantly improved in the last decades, even in high-volume centers patients still experience significant postoperative morbidity and full recovery after surgery takes longer than we think. In recent years, enhanced recovery pathways incorporating a large number of evidence-based perioperative interventions have proved to be beneficial i n t e r m s o f i m p rove d p o s t o p e ra t i ve o u t c o m e s, and accelerated patient recovery in the context of gastrointestinal, genitourinary and orthopedic surgery. The role of these pathways for pancreatic surgery is still unclear as high-quality randomized controlled trials are lacking. To date, non-randomized studies have shown that care pathways for pancreaticoduodenectomy and distal pancreatectomy are safe with no difference in postoperative morbidity, leading to early discharge and no increase in hospital readmissions. Hospital costs are reduced due to better organization of care and resource utilization. However, further research is needed to clarify the effect of enhanced recovery pathways on patient recovery and post-discharge outcomes following pancreatic resection. Future studies should be prospective and follow recent recommendations for the design and reporting of enhanced recovery pathways.Nicolò Pecorelli Sara Nobile Stefano Partelli Luca Cardinali Stefano Crippa Gianpaolo Balzano Luigi Beretta Massimo Falconi 2016World Journal of Gastroenterology2016,22,28:2
2肝切除术患者围术期发生高血糖的相关因素及乌司他丁的干预效果显示文摘目的探讨肝切除术患者围术期发生高血糖的相关因素及乌司他丁的干预效果。方法肝切除术患者100例随机分为干预组和对照组各50例,均采用全身麻醉方式,观察组麻醉开始前和手术开始前给予乌司他丁,对照组给予20 ml生理盐水,检查两组手术切皮前(T0)、切肝后即刻(T1)、切除肝脏后20 min(T2)、缝合即刻(T3)、术后第1天(T4)和术后第2天(T5)血糖水平,并分析高血糖发生的危险因素。结果两组T1、T2、T3、T4和T5血糖水平差异显著(P<0.05);与T0比较,两组血糖逐渐升高,至T3最高,T4、T5降低,观察组上升和下降幅度比对照组更明显(P<0.05)。术中出血量、手术切除范围(肝段切除,联合肝段切除)和具有糖尿病史是肝切除术发生高血糖的独立危险因素(P<0.05)。结论乌司他丁可以明显预防肝切除术后血糖升高。刘丽丽 李笃竽 王涛 孙虎 徐志新 2015中国老年学杂志2015,35,20:2
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