共被期刊论文引用了2次
您的检索式：您选中1篇文献正在查看引证文献汇总
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Antioxidant and antiglycation properties of different solvent extracts from Chinese olive(Canarium album L.) fruit显示文摘Objective:To evaluate the antioxidant activity,antiglycation property,and bioactivc components content of different solvent extracts from Chinese olive(Canarium album L.) fruit.Methods:The dry powder of Chinese olive fruit was extracted with different solvents,i.e.,water,water/ethanol(1/1,v/v),ethanol,methanol,acetone and ethyl acetate.The total phenolic,total flavonoids and total triterpenoids contents of various extracts were determined by spectrophotometric methods.Phenolic compounds were identified by high performance liquid chromatography.The assayed antioxidant activity was determined in vitro models such as antioxidant capacity by radical scavenging activity using 2,2'-azino-bLs(3-ethylbenzthiazoline-6-sulfonic acid)(ABTS),l,l-diphenyl-2-picryl- hydrazyl(DPPH) and nitrite oxide methods,chelating activity on metal ions,lipid and protein peroxidation methods.In vitro glucosebovine serum albumin assay was used to evaluate the antiglycation of various extracts.Results:The water/ethanol extracts of Chinese olive fruit exerted significant scavenging effects on free radicals and strong inhibitory effects on advanced glycation end products formation.The Chinese olive fruit extracts were rich in phenolic compounds and triterpenoids.Gallic acid,ferulic acid and rutin were identified from the water/ethanol extracts.Correlation analysis indicated that there was a linear relationship between the antioxidant potency,free radical scavenging ability and phenolic compounds content of the Chinese olive fruit extracts.Conclusions:Chinese olive fruit could be a natural candidate for studies of dietary complement to diabetes treatment since it combines antioxidant and antiglycation activities. | Chiung-Tsun Kuo Tzu-Hao Liu Tai-Hao Hsu Fang-Yi Lin Hui-Yin Chen | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，12： | 17 |
| 2 | 表没食子儿茶素没食子酸酯对2型糖尿病大鼠主动脉Ⅰ、Ⅳ型胶原及纤维连接蛋白表达的影响显示文摘目的探讨表没食子儿茶素没食子酸酯(EGCG)对2型糖尿病大鼠主动脉Ⅰ、Ⅳ型胶原(ColⅠ、ColⅣ)、纤维连接蛋白(FN)表达的影响及可能机制。方法通过高脂喂养加腹腔注射小剂量链脲佐菌素(STZ)构建2型糖尿病大鼠模型。雄性SD大鼠分为正常对照组8只,模型组、EGCG低、中、高剂量组,每组10只。EGCG给药组大鼠每周灌胃7 d。实验结束后检测大鼠血液血糖(GLU)、糖化血红蛋白(GHb)、糖化血清蛋白(GSP)和主动脉超氧化物歧化酶(SOD)、丙二醛(MDA)、ColⅠ、ColⅣ、FN水平的变化。结果与正常对照组相比,糖尿病模型组的血液GLU、GHb、GSP水平和主动脉氧化应激水平及主动脉ColⅠ、ColⅣ、FN表达均显著升高(P<0.01);与模型组相比,EGCG中、高剂量组血液GLU、GHb、GSP水平和主动脉氧化应激水平及主动脉ColⅠ表达均显著降低(P<0.05),EGCG高剂量组主动脉ColⅣ、FN表达显著降低(P<0.05)。结论 EGCG对2型糖尿病大鼠主动脉胶原合成异常增加具有明显的改善作用,机制可能与EGCG的降血糖、抗氧化及降低氧化应激下游与胶原代谢相关的信号通路效应有关。 | 侯改霞 赵功炎 习雪峰 肖国强 | 2015 | 中国老年学杂志2015，35，22： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员