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| 1 | 中山某医院2009-2014年住院孕妇人群乙型肝炎血清流行病学动态研究显示文摘目的了解流动人口密集的中山南朗医院住院孕妇人群乙型肝炎(乙肝)血清流行病学特点,评估乙肝预防措施的效果。方法回顾性分析中山市南朗医院2009-2014年住院的孕妇临床数据,用ELISA方法检测孕妇及相关新生儿的乙肝血清标记物,分层分析不同地区和年龄的孕妇乙肝表面抗原(HBsAg)携带率。结果 2009-2014年中山市南朗医院住院孕妇主要为省外户籍孕妇66.3%(4 666/7 034),HBsAg携带率8.63%(607/7 034)。分层分析中山市户籍(9.09%)、省内市外户籍(10.79%)和省外户籍(7.97%)住院孕妇的HBsAg携带率差异有统计学意义(P=0.008);省外户籍2014年孕妇HBsAg携带率较2009年明显升高(10.83%vs 5.53%,P=0.005)。HBsAg阳性孕妇的新生儿HBsAg携带率从2009-2011年的11.58%下降至2012-2014年的6.42%(P=0.033)。结论中山市南朗医院住院孕妇HBsAg总体携带率高,省内和省外孕妇之间HBsAg携带率均呈现地区不均衡,流动孕妇人群的HBV感染应该得到进一步监控。 | 侯枫林 汪为刚 翟银生 高阳 江凯 张慧 马世武 | 2015 | 中国病毒病杂志2015，5，4： | 5 |
| 2 | Three decades of hepatitis B control with vaccination显示文摘Hepatitis B virus(HBV) continues to represent a major health problem and can lead to acute liver failure, acute hepatitis, chronic carriership, chronic hepatitis of HBV, liver cirrhosis, liver cancer, liver transplantation and death. There is a marked difference in the geographic distribution of carriers. More than 240 million people worldwide are chronic HBV carriers. Mother-to-child transmission remains the most important mechanism of infection in countries with a high prevalence of HBV. Percutaneous/parenteral transmission and unsafe sexual practices are important mode of spread transmission of HBV in other countries. Vaccination against HBV is the gold measure for primary prevention and control of the disease. Currently, 179 countries have added HBV vaccination to their routine vaccination programs with great results. Neonatal immunization with HBV vaccine has been one of the most highly effective measures in public health and the first anti-cancer program to be launched. In this paper we review the achievements for the last three decades. | Liliane C Meireles Rui Tato Marinho Pierre Van Damme | 2015 | World Journal of Hepatology2015，7，18： | 5 |
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