维普中文期刊产品整合服务
共被期刊论文引用了3次 您的检索式:您选中1篇文献正在查看引证文献汇总
    题名 作者 年代 出处 被引量
1肠道微生态在克罗恩病发病中的作用以及治疗前景显示文摘克罗恩病(CD)的致病因素和发病机制至今尚未完全阐明,目前普遍认为其由遗传因素、免疫功能紊乱、肠道屏障功能障碍和肠道微生态改变等多因素所致。肠道微生态与CD发病的关系日益受到关注。多项证据表明CD患者存在肠道微生态改变,肠道微生态改变与CD发生相关,调节肠道微生态对CD有治疗作用。本文就肠道微生态与CD发病的关系以及治疗前景作一综述。楼俪泓 曾悦 王兴鹏 2016胃肠病学2016,21,2:5
2粪菌移植的方法学及其治疗炎症性肠病的研究进展显示文摘炎症性肠病(IBD)是一组病因尚不明确的慢性非特异性肠道炎症性疾病,越来越多的证据表明肠道微生态在IBD发病中起有重要作用。粪菌移植(FMT)作为重建肠道菌群的微生态治疗方法,对多种胃肠道和代谢性疾病的治疗有效。本文主要针对FMT的方法学研究及其在IBD治疗中的应用进展作一综述。向杰 张发明 黄光明 2016胃肠病学2016,21,2:5
3Host-microbiome interaction in Crohn's disease: A familiar or familial issue?显示文摘An impaired interaction between the gut and the intestinal microbiome is likely to be the key element in the pathogenesis of Crohn's disease(CD). Family studies have provided invaluable information on CD pathogenesis and on its etiology. Relatives share the same genetic risk of developing the disease as affected subjects. Relatives also exhibit similar features relating to their host-microbiome interaction, namely genetic variants in loci involved in detecting bacteria, a greater seroreactivity to microbial components, and an impaired intestinal permeability. The burden of environmental factors such as cigarette smoking and dysbiosis also seems to be particularly relevant in these genetically predisposed subjects. Diet is emerging as an important factor and could account for the changing epidemiology of CD in recent years. Despite the pivotal role of genetics in the disease's pathogenesis(especially in familial CD), screening tests in healthy relatives cannot be recommended.Andrea Michielan Renata D’Incà 2015World Journal of Gastrointestinal Pathophysiology2015,6,4:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费