维普中文期刊产品整合服务
共被期刊论文引用了4次 您的检索式:您选中1篇文献正在查看引证文献汇总
    题名 作者 年代 出处 被引量
1Gastric cancer: Current status of lymph node dissection显示文摘D2 procedure has been accepted in Far East as the standard treatment for both early(EGC) and advanced gastric cancer(AGC) for many decades. Recently EGC has been successfully treated with endoscopy by endoscopic mucosal resection or endoscopic submucosal dissection, when restricted or extended Gotoda's criteria can be applied and D1+ surgery is offered only to patients not fitted for less invasive treatment. Furthermore, two randomised controlled trials(RCTs) have been demonstrating the non inferiority of minimally invasive technique as compared to standard open surgery for the treatment of early cases and recently the feasibility of adequate D1+ dissection has been demonstrated also for the robot assisted technique. In case of AGC the debate on the extent of nodal dissection has been open for many decades. While D2 gastrectomy was performed as the standard procedure in eastern countries, mostly based on observational and retrospective studies, in the west the Medical Research Council(MRC), Dutch and Italian RCTs have been conducted to show a survival benefit of D2 over D1 with evidence based medicine. Unfortunately both the MRC and the Dutch trials failed to show a survival benefit after the D2 procedure, mostly due to the significant increase of postoperative morbidity and mortality, which was referred to splenopancreatectomy. Only 15 years after the conclusion of its accrual, the Dutch trial could report a significant decrease of recur-rence after D2 procedure. Recently the long term survival analysis of the Italian RCT could demonstrate a benefit for patients with positive nodes treated with D2 gastrectomy without splenopancreatectomy. As nowadays also in western countries D2 procedure can be done safely with pancreas preserving technique and without preventive splenectomy, it has been suggested in several national guidelines as the recommended procedure for patients with AGC.Maurizio Degiuli Giovanni De Manzoni Alberto Di Leo Domenico D'Ugo Erica Galasso Daniele Marrelli Roberto Petrioli Karol Polom Franco Roviello Francesco Santullo Mario Morino 2016World Journal of Gastroenterology2016,22,10:29
2Treatment modalities for early gastric cancer显示文摘Different treatment modalities have been proposed in the treatment of early gastric cancer(EGC). Endoscopic resection(ER) is an established treatment that allows curative treatment, in selected cases. In addition, ER allows for an accurate histological staging, which is crucial when deciding on the best treatment option for EGC. Recently, endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD) have become alternatives to surgery in early gastric cancer, mainly in Asian countries. Patients with 'standard' criteria can be successfully treated by EMR techniques. Those who meet 'expanded' criteria may benefit from treatment by ESD, reducing the need for surgery. Standardized ESD training system is imperative to promulgate effective and safe ESD technique to practices with limited expertise. Although endoscopic resection is an option in patients with EGC, surgical treatment continues to be a widespread therapeutic option worldwide. In this review we tried to point out the treatment modalities for early gastric cancer.Jesús Espinel Eugenia Pinedo Vanesa Ojeda Maria Guerra del Rio 2015World Journal of Gastrointestinal Endoscopy2015,7,12:11
3黏膜下剥离术治疗早期胃癌对患者血清Livin、EGF、IL-8水平的影响显示文摘目的观察内镜黏膜下剥离术(ESD)治疗早期胃癌(EGC)对患者血清抗凋亡因子(Livin)、表皮生长因子(EGF)及白介素-8(IL-8)水平的影响。方法将169例EGC患者随机分成2组,研究组行内镜ESD,对照组行常规开腹切除术。比较2组患者术中出血量、手术时间及住院时间。采用ELISA法检测并比较2组手术前后血清Livin、EGF及IL-8水平表达变化。结果研究组出血量少于对照组,手术时间和住院时间均短于对照组,差异均有统计学意义(P<0.05)。治疗前,2组患者血清Livin、EGF及IL-8表达水平差异无统计学意义;治疗后2组上述血清指标水平均明显降低,且研究组低于对照组,差异均有统计学意义(P<0.05)。结论内镜ESD治疗EGC具有术中出血少、手术时间及住院时间短的优势,同时可降低血清Livin、EGF、IL-8表达水平,值得在临床进一步推广应用。郭霄梅 杨希泉 王红娟 刘晓红 2016临床合理用药杂志2016,9,1:3
4色素内镜诊断早期胃癌的临床价值探究显示文摘目的探讨色素内镜诊断早期胃癌的临床价值。方法收集2012年2月-2014年12月来我院就诊的疑似早期胃癌患者184例,所有患者均给予常规内镜以及色素内镜检测,比较2种方法诊断早期胃癌的灵敏度、特异度和正确率。结果色素内镜的灵敏度和诊断正确率明显高于常规内镜,差异有统计学意义(P<0.05);但二者诊断特异度差异无统计学意义(P>0.05)。结论色素内镜可以有效地提高早期胃癌的检出率,具有较高的临床应用价值。郭霄梅 杨希泉 王红娟 刘晓红 2016临床合理用药杂志2016,9,7:2
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费