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| 1 | Aluminum potassium sulfate and tannic acid sclerotherapy for Goligher Grades Ⅱ and Ⅲ hemorrhoids: Results from a multicenter study显示文摘AIM: To show that aluminum potassium sulfate and tannic acid(ALTA) sclerotherapy has a high success rate for Grade Ⅱ and Ⅲ hemorrhoids.METHODS: This study was based on the clinical data of 604 patients with hemorrhoids who underwent ALTA sclerotherapy between January 2009 and February 2015. The objective of this study was to assess the efficacy of this treatment for Grades Ⅱ and Ⅲ hemorrhoids. Preoperative and postoperative symptoms, complications and success rate were all assessed retrospectively. Follow-up consisted of a simple questionnaire, physical examination and an anoscopy. Patients were followed-up at one day, one week, two weeks, one month, one year, two years, three years, four years and five years after the ALTA sclerotherapy.RESULTS: One hundred and sixty-nine patients were diagnosed with Grade Ⅱ hemorrhoids and 435 patients were diagnosed with Grade Ⅲ hemorrhoids. The one year, three year and five year cumulative success rates of ALTA sclerotherapy for Grades Ⅱ and Ⅲ hemo-rrhoids were 95.9% and 93.1%; 89.3% and 83.7%; and 89.3% and 78.2%, respectively. No significant differences were observed in the cumulative success rates after ALTA sclerotherapy between Grades Ⅱ and Ⅲ hemorrhoids(P = 0.09). There were forty-seven post-operative complications(low grade fever; anal pain; urinary retention; rectal ulcer; and others). No serious or life-threatening complications occurred and all cases improved through conservative treatment. At univariate analysis there were no predictive factors of failure.CONCLUSION: ALTA sclerotherapy has had a high success rate for Grade Ⅱ and Ⅲ hemorrhoids during five years of post-operative treatment. However, additional studies are needed to evaluate the efficacy of this ALTA sclerotherapy in the management of hemorrhoidal disease. | Hidenori Miyamoto Takenori Hada Gentaro Ishiyama Yoshito Ono Hideo Watanabe | 2016 | World Journal of Hepatology2016，8，20： | 10 |
| 2 | 多普勒引导痔动脉结扎术后肛门直肠压力的变化显示文摘目的观察多普勒引导痔动脉结扎术(DGHAL)后患者肛门直肠压力的变化。方法选取25例内痔患者,均行DGHAL,术前、术后3个月采用胃肠动力学检测系统进行肛门直肠测压检查,观察肛管静息压、肛管最大收缩压、排便弛缓反射、直肠肛管收缩反射、直肠肛管抑制反射、直肠初始感觉阈值、直肠排便感觉阈值、直肠最大耐受量变化。结果 25例行DGHAL患者术前、术后3个月的肛管静息压分别为(122.7±27.2)、(57.2±16.8)mm Hg,肛管最大收缩压分别为(210.7±26.1)、(145.4±16.5)mm Hg,直肠肛管抑制反射分别为(8.1±3.9)、(7.9±2.5)m L,直肠初始感觉阈值分别为(22.1±3.7)、(21.7±2.8)m L,直肠排便感觉阈值分别为(56.3±5.8)、(55.1±4.4)m L,直肠最大耐受量分别为(213.5±42.4)、(208.2±40.1)m L,直肠肛管收缩反射均存在,手术前后的肛管静息压、肛管最大收缩压比较,P均<0.05,其余指标比较差异无统计学意义。结论内痔患者DGHAL后肛管静息压、肛管最大收缩压明显降低。 | 蔡姮婧 秦澎湃 段宏岩 卞秀华 叶明 | 2015 | 山东医药2015，55，45： | 4 |
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