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1低剂量聚乙二醇电解质溶液分次肠道准备在老年人结肠镜检查中的效果观察显示文摘目的 :探讨低剂量(2 L)聚乙二醇(polyethylene glycol,PEG)电解质溶液分次肠道准备在老年人结肠镜检查中的应用效果。方法:将160例接受结肠镜检查的老年人随机分为两组,分次组(检查前一天晚上和检查当天早晨各予1 L PEG)和单次组(检查当天早晨予2 L PEG),各80例。比较两组的肠道准备质量、不良反应发生率、患者的依从性和耐受性,回盲部插管成功率及操作不良事件发生率。结果:两组的波士顿肠道准备量表(Boston bowel preparation scale,BBPS)分段评分和总分比较差异均无统计学意义(P>0.05)。分次组的恶心、呕吐、腹胀发生率明显低于单次组(P<0.05),完成肠道准备、认为肠道准备容易完成、愿意再次肠道准备的比率均明显高于单次组(P<0.05)。两组的回盲部插管成功率差异无统计学意义(P>0.05),且均无结肠镜操作不良事件发生。结论:低剂量PEG电解质溶液分次肠道准备对老年人的肠道清洁效果好,不良反应少,患者依从性和耐受性高,值得在老年人结肠镜检查前肠道准备中推广应用。华婷琰 陈志荣 闵寒 2015南通大学学报(医学版)2015,35,5:6
2Electrolyte changes after bowel preparation for colonoscopy:A randomized controlled multicenter trial显示文摘AIM:To investigate the electrolyte changes between 2-L polyethylene glycol with ascorbic acid 20 g(PEGAsc) and 4-L PEG solutions.METHODS:From August 2012 to February 2013,a total of 226 patients were enrolled at four tertiary hospitals.All patients were randomly allocated to a PEG-Asc group or a 4-L PEG.Before colonoscopy,patients completed a questionnaire to assess bowel preparation-related symptoms,satisfaction,and willingness.Endoscopists assessed the bowel preparation using the Boston Bowel Preparation Scale(BBPS).In addition,blood tests,including serum electrolytes,serum osmolarity,and urine osmolarity were evaluated both before and after the procedure.RESULTS:A total of 226 patients were analyzed.BBPS scores were similar and the adequate bowel preparation rate(BBPS≥6)was not different between the two groups(PEG-Asc vs 4-L PEG,73.2%vs 76.3%,P=0.760).Bowel preparation-related symptoms also were not different between the two groups.The taste of PEG-Asc was better(41.1%vs 16.7%,P<0.001),and the willingness to undergo repeated bowel preparation was higher in the PEG-Asc group(73.2%vs 59.3%,P=0.027)than in 4-L PEG.There were no significant changes in serum electrolytes in either group.CONCLUSION:In this multicenter trial,bowel preparation with PEG-Asc was better than 4-L PEG in terms of patient satisfaction,with similar degrees of bowel preparation and electrolyte changes.Kyong Joo Lee Hong Jun Park Hyun-Soo Kim Kwang Ho Baik Yeon Soo Kim Sung Chul Park Hyun Il Seo 2015World Journal of Gastroenterology2015,21,10:3
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