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| 1 | 肛瘘手术治疗新进展显示文摘肛瘘是直肠或肛管与肛周皮肤相通的肉芽肿性通道,由内口、外口及窦道组成,是肛门周围间隙感染的慢性阶段。国际上常用的肛瘘分类方式为高位肛瘘和低位肛瘘分类方式(瘘管通过肛门外括约肌的下1/3称为低位肛瘘)以及Park分类方式~[1](即:A.括约肌间瘘;B.经括约肌肛瘘;C.括约肌上方肛瘘;D.括约肌外侧肛瘘)。肛瘘治疗首选手术,传统术式治疗低位肛瘘以瘘管切开术、瘘管切除术为主。 | 覃杰 张森 | 2015 | 结直肠肛门外科2015,21,6: | 10 |
| 2 | PERFACT procedure:A new concept to treat highly complex anal fistula显示文摘AIM: To check the efficacy of the PERFACT procedure in highly complex fistula-in-ano.METHODS: The PERFACT procedure(proximal superficial cauterization, emptying regularly fistula tracts and curettage of tracts) entails two steps: superficial cauterization of mucosa at and around the internal opening and keeping all the tracts clean. The principle is to permanently close the internal opening by granulation tissue. This is achieved by superficial electrocauterization at and around the internal opening and subsequently allowing the wound to heal by secondary intention. Along with this, all the tracts are curetted and it is ensured that they remain empty and clean in the postoperative period until they heal completely. The latter step also facilitates the closure of the internal opening by preventing collected fluid in the tracts from entering the internal opening and thus not letting it close. Objective incontinence scoring was done preoperatively and 3 mo after the operation.RESULTS: Fifty-one patients with complex fistula-inano were prospectively enrolled. The median followup was 9 mo(5-14 mo). The mean age was 42.7 ± 11.3 years. Male:female ratio was 43:8. Fistula was recurrent in 76.5%(39/51), horseshoe in 50.1%(26/51), had multiple tracts in 52.9%(27/51), had an associated abscess in 41.2%(21/51), was anterior in 33.3%(17/51), the internal opening was not found in 15.7%(8/51) and 9.8%(5/51) of fistulas had a supralevator extension. Seven patients were excluded(5 lost to follow up, 2 with tuberculosis leading to/associated with fistula-in-ano). The success rate was 79.5%(35/44) and the recurrence rate was 20.5%(9/44). Out of these recurrences, three underwent reoperation(2 PERFACT procedure, 1 fistulotomy) and all three were successful. Thus, the overall success rate was 86.4%. The only complication was a non-healing tract in 9.1%(4/44) of patients. There was no significant change in objective incontinence scores three months after the operation. The pain was minimal, with all patients resuming their normal activities within 72 h of the operation.CONCLUSION: The PERFACT procedure is a new effective method for complex fistula-in-ano, effective even in fistula associated with abscess, supralevator fistula-in-ano and where the internal opening is nonlocalizable. | Pankaj Garg Mahak Garg | 2015 | World Journal of Gastroenterology2015,21,13: | 7 |
| 3 | 生物支架材料治疗肛瘘的研究进展显示文摘近年来,随着分子生物学、细胞生物学和生物组织工程学等技术的发展,生物支架材料作为一种新兴技术渐渐在临床外科等各个领域获得普遍应用。目前很多学者经过实验研究证明了使用生物支架材料制作成的肛瘘栓(Anal Fistula Plug,AFP)在临床上有着广大应用价值。笔者通过查阅国内外生物支架材料在治疗肛瘘方面的相关文献,对人工合成材料、天然生物衍生材料以及复合材料的应用与研究做一综述,并展望了其未来的发展方向。 | 谢宏 禹正杨 | 2015 | 大家健康(学术版)2015,,5: | 3 |
| 4 | Prospective evaluation of a new device for the treatment of anal fistulas显示文摘AIM: To evaluate the safety of the implantation of a new device for the treatment of anal fistulas. The short-term clinical efficacy was also assessed. METHODS: This study took place at a tertiary care university hospital. Patients with a complex anal fistula of cryptoglandular origin were enrolled in the study and were treated with insertion of the new device. All patients were evaluated by clinical and physical examination, including an endoanal ultrasound at the baseline, and then at the 2 wk and 1, 2, 3 and 6-mo follow-up visits. RESULTS: Morbidity, continence status, and success rate were the main outcome measures. Ten patients underwent the placement of the new device. The fistulas were transphincteric in eight patients and extrasphincteric in the remaining two. The median duration of the surgical procedure was 34.5(range, 27-42) min. Neither intra- nor postoperative complications occurred, and all patients were discharged the day after the procedure. At the 6-mo follow-up evaluation, the final success rate was 70%. Three failures were registered: a device expulsion(on the 10 th postoperative day), the persistence of inflammatory tissue around the fistula tract(at the 2-mo follow up), and the persistence of serum discharge(at the 6-mo follow up). No patient experienced any change incontinence, as assessed by the Cleveland Clinic Fecal Incontinence score. CONCLUSION: The technical procedure is simple and has low risk of perioperative morbidity. The pre- and post-operative continence status did not change in any of the patients. The initial results at the 6-mo follow up seem to be promising. However, a longer follow-up period and a larger sample size are needed to confirm these preliminary results. | Carlo Ratto Francesco Litta Lorenza Donisi Angelo Parello | 2016 | World Journal of Gastroenterology2016,22,30: | 2 |
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