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| 1 | Oral pathology in inflammatory bowel disease显示文摘The incidence of inflammatory bowel diseases(IBD)-Crohn's disease(CD) and ulcerative colitis(UC)- has been increasing on a global scale, and progressively, more gastroenterologists will be included in the diagnosis and treatment of IBD. Although IBD primarily affects the intestinal tract, extraintestinal manifestations of the disease are often apparent, including in the oral cavity, especially in CD. Specific oral manifestations in patients with CD are as follows: indurate mucosal tags, cobblestoning and mucogingivitis, deep linear ulcerations and lip swelling with vertical fissures. The most common non-specific manifestations, such as aphthous stomatitis and angular cheilitis, occur in both diseases, while pyostomatitis vegetans is more pronounced in patients with UC. Non-specific lesions in the oral cavity can also be the result of malnutrition and drugs. Malnutrition, followed by anemia and mineral and vitamin deficiency, affects the oral cavity and teeth. Furthermore, all of the drug classes that are applied to the treatment of inflammatory bowel diseases can lead to alterations in the oral cavity due to the direct toxic effects of the drugs on oral tissues, as well as indirect immunosuppressive effects with a risk of developing opportunistic infections or bone marrow suppression. There is a higher occurrence of malignant diseases in patients with IBD, which is related to the disease itself and to the IBD-related therapy with a possible oral pathology. Treatment of oral lesions includes treatment of the alterations in the oral cavity according to the etiology together with treatment of the primary intestinal disease, which requires adequate knowledge and a strong cooperation between gastroenterologists and specialists in oral medicine. | miranda muhvic-urek marija tomac-stojmenovic brankica mijandrusic-sincic | 2016 | World Journal of Gastroenterology2016，22，25： | 11 |
| 2 | Nd:YAG激光治疗放射性口腔溃疡的临床疗效显示文摘对比Nd:YAG激光与碘酚治疗放射性口腔溃疡的临床疗效,为选择治疗放射性口腔溃疡的有效方法提供依据。选择临床确诊为放射性口腔溃疡的患者36例,共186个溃疡,按就诊顺序使用奇数偶数法分组。奇数组为实验组,使用Nd:YAG激光进行治疗;偶数组为对照组,使用碘酚进行治疗,比较两组治疗前后患者的疼痛指数,溃疡的愈合时间及溃疡治疗的有效率。激光治疗组疼痛指数,溃疡的愈合时间均少于碘酚治疗组,两者比较差异有显著性(P<0.05)。而两者治疗的有效率相比没有统计学意义(P>0.05)。Nd:YAG激光治疗放射性口腔溃疡可明显缓解患者疼痛,促进溃疡的愈合,值得临床推广使用。 | 李灵 陈俊宏 邓蔓菁 | 2015 | 激光杂志2015，36，5： | 3 |
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