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| 1 | 多不饱和脂肪酸预防心房颤动复发的荟萃分析显示文摘目的:系统评价多不饱和脂肪酸(polyunsaturated fatty acids,PUFA)预防房颤复发的有效性。方法:检索Medline、EMBASE、Elsevier、Cochrane等数据库,收集PUFA预防房颤复发的随机对照试验(RCT),2位研究人员独立检索和评价文献,应用RevMan 5.0和Stata 10.0进行数据统计学处理。结果:6项RCT研究共包括1 839例患者纳入该荟萃分析。结果提示PUFA治疗并不能预防阵发性房颤及持续性房颤复律后复发(RR=0.96,95%CI为0.75~1.22,P=0.74),亚组分析发现,复律及随访前PUFA治疗至少28 d的亚组中,PUFA能明显减少随访过程中房颤的复发(RR=0.720,95%CI为0.622~0.835,P<0.01)。结论:荟萃分析结果显示PUFA治疗不能降低房颤复发率。 | 李晓丽 张宝伟 刘玲玲 赵龙 沈冬丽 孔彪 张国辉 | 2014 | 江苏大学学报(医学版)2014，24，3： | 2 |
| 2 | Omega 3 and atrial fibrillation:Where are we?显示文摘Anti-arrhythmic properties of n-3 polyunsaturated fatty acids, at least in part mediated by anti-oxidant, anti-inflammatory and anti-fibrotic power, have been widely proved. Effect of fish oil on atrial fibrillation, both in primary and in secondary prevention and after cardiac surgery, are controversial, mostly due to lack of homogeneity between studies but also due to individual variability in response to fatty acids administration. Inclusion of measurement of incorporation of fish oil into cell membranes, appears to be essential in future studies, to assess their antiarrhythmic effect. | Annamaria Martino Laura Pezzi Roberta Magnano Elisa Salustri Maria Penco Leonardo Calo' | 2016 | World Journal of Cardiology2016，8，2： | 0 |
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