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| 1 | 广州地区儿童患者EB病毒感染分析显示文摘目的分析儿童患者EB病毒(EBV)感染状况。方法收集广州地区2013年妇女儿童医疗中心就诊儿童患者EBV感染相关抗体数据,分别对EBV患儿年龄、所患疾病种类、月份分布等进行统计学分析。结果儿童患者7 582例,总体EBVCA-IgM感染率16.97%,各年龄段分别为0~<3岁15.92%、3~<6岁22.53%、6~<10岁16.69%、10岁以上8.30%;EBV感染疾病比例最高的是传染性单核细胞增多症,其次是呼吸道感染疾病;3月份和9月份EBV感染率最高。EBV系列抗体检测阳性率分别为EBVCA-IgM 19.11%,EBVCA-IgG 61.57%、EBNA-1-IgG 53.76%、EBVEA-IgG 9.50%,EBVCA-IgG阳性和EBNA-1-IgG阳性组合比例最高,占39.57%。结论 EBV是儿童感染重要的病原体;有39.57%的儿童过往曾经感染EB病毒;随着年龄的增长,EBV感染比例有下降。 | 林涛 陈翊 连广琬 陈焕辉 刘晓敏 | 2014 | 国际检验医学杂志2014，35，15： | 7 |
| 2 | Cytomegalovirus related fatal duodenal diverticular bleeding: Case report and literature review显示文摘Involvement of gastrointestinal tract by cytomegalovirus(CMV) is common. CMV infections mainly run their course without any clinical signs in immunocompetent hosts. In contrast, CMV can cause severe infections with serious consequences in a immunocompromised state typically associated with organ transplants, highly immunosuppressive cancer chemotherapy, advanced HIV infection or treatment with corticosteroids. The incidence and severity of these manifestations of CMV is directly proportional with the degree of cellular immune dysfunction, i.e., CD8+ Cytotoxic T-cell response. Clinical manifestations of CMV can become apparent in different situations including reactivation of CMV from latency, primary infection in a seronegative host, or exposure of a seropositive host to a new strain of CMV. As the clinical signs of CMV in immunodeficient patients are usually sparse, physicians should be highly vigilant about CMV infection, a treatable condition that otherwise is associated with significant mortality. Here we report a rare case of severe gastrointestinal CMV infection with sustained immunodeficiency secondary to treatment with steroids manifesting as fatal duodenal diverticular bleeding. | Jasbir Makker Bharat Bajantri Sailaja Sakam Sridhar Chilimuri | 2016 | World Journal of Gastroenterology2016，22，31： | 0 |
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