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1Inflammatory bowel disease and thromboembolism显示文摘Patients with inflammatory bowel disease(IBD) have an increased risk of vascular complications. Thromboembolic complications,both venous and arterial,are serious extraintestinal manifestations complicating the course of IBD and can lead to significant morbidity and mortality. Patients with IBD are more prone to Thromboembolic complications and IBD per se is a risk factor for thromboembolic disease. Data suggest that thrombosis is a specific feature of IBD that can be involved in both the occurrence of thromboembolic events and the pathogenesis of the disease. The exact etiology for this special association between IBD and thromboembolism is as yet unknown,but it is thought that multiple acquired and inherited factors are interacting and producing the increased tendency for thrombosis in the local intestinal microvasculature,as well as in the systemic circulation. Clinicians' awareness of the risks,and their ability to promptly diagnose and manage TEs are of vital importance. In this review we discuss how thromboembolic disease is related to IBD,specifically focusing on:(1) the epidemiology and clinical features of thromboembolic complications in IBD;(2) the pathophysiology of thrombosis in IBD;and(3) strategies for the prevention and management of thromboembolic complications in IBD patients.Petros Zezos Georgios Kouklakis Fred Saibil 2014World Journal of Gastroenterology2014,20,38:12
2老年肺栓塞诊治进展显示文摘肺栓塞(pulmonary embolism,PE)是内源性或外源性栓子阻塞肺动脉引起肺循环障碍的临床和病理生理综合征,包括肺血栓栓塞症(pulmonary thromboembolism,PTE)、脂肪栓塞综合征、羊水栓塞、空气栓塞、肿瘤栓塞等。其中PTE是最常见的PE类型,占PE的绝大多数,通常所称的PE即指PTE。深静脉血栓形成(deep venous thrombosis,陈磊 吴剑卿 2015中华老年病研究电子杂志2015,2,4:5
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