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| 1 | How important is donor age in liver transplantation?显示文摘The age of liver donors has been increasing in the past several years because of a donor shortage. In the United States, 33% of donors are age 50 years or older, as are more than 50% in some European countries. The impact of donor age on liver transplantation(LT) has been analyzed in several studies with contradictory conclusions. Nevertheless, recent analyses of the largest databases demonstrate that having an older donor is a risk factor for graft failure. Donor age is included as a risk factor in the more relevant graft survival scores, such as the Donor Risk Index, donor age and Model for End-stage Liver Disease, Survival Outcomes Following Liver Transplantation, and the Balance of Risk. The use of old donors is related to an increased rate of biliary complications and hepatitis C virus-related graft failure. Although liver function does not seem to be significantly affected by age, the incidence of several liver diseases increases with age, and the capacity of the liver to manage or overcome liver diseases or external injuries decreases. In this paper, the importance of age in LT outcomes, the role of donor age as a risk factor, and the influence of aging on liver regeneration are reviewed. | Alberto Lué Estela Solanas Pedro Baptista Sara Lorente Juan J Araiz Agustin Garcia-Gil M Trinidad Serrano | 2016 | World Journal of Gastroenterology2016，22，21： | 10 |
| 2 | 肝移植术后患者的个体化健康管理显示文摘目的评价个体化健康管理方式对肝移植术后患者长期存活及生存质量的影响。方法回顾性分析2006年1月至2009年1月在我中心随访调查的肝移植术后患者共374例。所有患者均签署知情同意书,研究符合伦理规定及要求。将374例患者随机分为个体化健康管理实验组和常用药物治疗对照组,实验组在随访过程中采用个体化健康管理方式干预,对照组不进行干预;比较两组不良事件发生率。结果两组患者不良事件的发生率差异具有统计学意义(17.4%比52.2%,χ2=8.326,P<0.05)。结论个体化健康管理方式能更好地提高肝移植术后患者的存活率和生活质量。 | 王颖 赵文 陈新国 毛莎 | 2015 | 实用器官移植电子杂志2015，3，3： | 7 |
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