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| 1 | 某部官兵赴藏演练前后血尿酸水平变化分析显示文摘目的通过分析高原演练前后官兵血尿酸水平变化,探讨血尿酸水平改变对官兵健康的影响,为高原卫勤保障的疾病预防措施提供依据。方法抽取静脉血5 ml,在雅培Ci8200生化免疫自动化分析工作站完成,应用SPSS19.0统计软件对尿酸结果进行分析。结果赴藏前已经有14.2%的人员出现高尿酸血症。赴藏后高尿酸血症的人员增加到48.6%,赴藏前后血尿酸水平有显著差异(P<0.01)。结论 1赴藏前人员中有高尿酸血症;2急进高原官兵血尿酸水平明显升高,加强高尿酸血症的预防治疗,是高原卫勤保障工作的重点。 | 王会英 杨廷桐 | 2015 | 实用医药杂志2015，32，9： | 1 |
| 2 | Study the effect of kidney stones on serum xanthine oxidase, ecto-5'-nucleotidase activity and E3 SUMO-protein ligase NSE2(NSMCE2) in Malaysian individuals显示文摘Objective: To verify possible relations between 5'-nucleotidase, xanthine oxidase to E3 small ubiquitin-like modifier-protein ligase non structural maintenance of chromosomes elements 2 in sera patients with kidney stones and to evaluate the possibility of a new biomarker for the evaluation of kidney damage. Methods: A sixty patients with known kidney stones who appeared the government health clinics in Kuantan–Pahang and fifty apparently healthy were taken as control group. The 5'-nucleotidase,xanthine oxidase and other biochemical parameters were measured by colorimetric tests. The serum NSMCE2 were measured by enzyme linked immunosorbent assay.Results: The mean serum xanthine oxidase [(39.98±19.70) IU/L] and ecto-5'-nucleotidase activity(40.03±9.53 IU/L) were significantly higher than the controls' levels of(18.04 ±6.26) and(16.06 ±4.61) IU/L respectively. There were 85.00% and 83.33%, of patients with kidney stones who had abnormal ecto-5'-nucleotidase activity and uric acid respectively while xanthine oxidase activity was less sensitive 58.33%.Conclusions: The present study suggests that the increase in serum of xanthine oxidase,ecto-5'-nucleotidase activities E3 small ubiquitin-like modifier-protein ligase NSE2 concentration can be used as biomarkers for diagnosis of kidney damage in patients with kidney stone,also in developments of change DNA damage and inflammation disorders in these patients. | Faridah Yusof Atheer Awad Mehde Wesen Adel Mehdi Hamid Ghazali Azlina Abd Rahman | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，8： | 0 |
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