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1植物多酚抗肥胖作用的研究进展显示文摘植物多酚是一类广泛存在于植物体内的次生代谢产物,具有抗癌、抗氧化、抗菌、抗病毒等生物活性。随着肥胖发生率的急速增加,抗肥胖药物或功能性食品的研究成为了热点。植物多酚类化合物抗肥胖效果显著,近年来其抗肥胖机理也得到了进一步的阐明,本文对植物多酚在调节代谢酶活性、刺激机体产热、调节机体信号和肠道微生物菌群方面的抗肥胖研究进展进行综述。高航 徐虹 2014食品科学2014,35,21:26
2Inhibition of α-amylase and α-glucosidase activities by ethanolic extract of Telfairia occidentalis (fluted pumpkin) leaf显示文摘Objective:To investigate the inhibitory effect of Telfairia occidentalis Hook f.(Curcubitaceae)(T.occidentalis)leaf on key enzyme linked to type-2 diabetes(α-amylase andα-glucosidase)as well as assess the effect of blanching(a commonly practiced food processing technique)of the vegetable on these key enzymes.Methods:Fresh leaves of T.occidentalis were blanched in hot water for 10 minutes,and the extracts of both the fresh and blanched vegetables were prepared and used for subsequent analysis.The inhibitory effect of the extract onα-amylase andα-glucosidase activities as well as some antioxidant parameter was determined in vitro.Results:The result revealed that unprocessed T.occidentalis leaf reduce Fe^(3+)to Fe^(2+)and also inhibitedα-amylase andα-glucosidase activities in a dose dependent manner.However,blanching of the leafy vegetables caused a significant(P<0.05)increase in the antioxidant properties but decrease their ability to inhibitα-amylase andα-glucosidase activities.Conclusions:This antioxidant properties and enzyme inhibition could be part of the mechanism by which they are used in the treatment/prevention of type-2 diabetes.However,the blanched vegetable reduces their ability to inhibit bothα-amylase andα-glucosidase activity in vitro.G Oboh AJ Akinyemi AO Ademiluyi 2012Asian Pacific Journal of Tropical Biomedicine2012,2,9:0
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