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1Coronary CT angiography:Beyond morphological stenosis analysis显示文摘Rapid technological developments in computed tomography(CT)imaging technique have made coronary CT angiography an attractive imaging tool in the detection of coronary artery disease.Despite visualization of excellent anatomical details of the coronary lumen changes,coronary CT angiography does not provide hemodynamic changes caused by presence of plaques.Computational fluid dynamics(CFD)is a widely used method in the mechanical engineering field to solve complex problems through analysing fluid flow,heat transfer and associated phenomena by using computer simulations.In recent years,CFD is increasingly used in biomedical research due to high performance hardware and software.CFD techniques have been used to study cardiovascular hemodynamics through simulation tools to assist in predicting the behaviour of circulatory blood flow inside the human body.Blood flow plays a key role in the localization and progression of coronary artery disease.CFD simulation based on 3D lumina reconstructions can be used to analyse the local flow fields and flow profiling due to changes of vascular geometry,thus,identifying risk factors for development of coronary artery disease.The purpose of this article is to provide an overview of the coronary CT-derived CFD applications in coronary artery disease.Akmal Sabarudin Zhonghua Sun 2013World Journal of Cardiology2013,5,12:2
2Coronary CT angiography:Dose reduction strategies显示文摘With the introduction of 64- and post-64 slice computed tomography(CT)technology,coronary CT angiography has been increasingly used as a less invasive modality for the diagnosis of coronary artery disease.Despite its high diagnostic value and promising results compared to invasive coronary angiography,coronary CT angiography is associated with high radiation dose,leading to potential risk of radiation-induced cancer.A variety of dose-reduction strategies have been reported recently to reduce radiation dose with effective outcomes having been achieved.This article presents an overview of the various methods currently used for radiation dose reduction.Akmal Sabarudin Zhonghua Sun 2013World Journal of Cardiology2013,5,12:2
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