|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 生活方式与饮食习惯对胃食管反流的影响显示文摘胃食管反流病(gastroesophageal reflux disease,GERD)是由于胃和(或)十二指肠内容物反流至食管引起反酸、烧心等临床症状.不良的生活方式和饮食习惯可影响胃食管反流的发生[1].在2008年更新的亚太地区GERD处理共识治疗规则[2]指出,改变生活方式有助于GERD患者症状的控制.有学者认为,临床研究中20%~30%安慰剂有效者源自生活方式的改变,但仍未有统一结论.虽然改变生活方式不足以控制大多数GERD患者的症状,但却可以减少质子泵抑制剂的用量,减少治疗费用.故有必要了解饮食冈素与GERD发生的相关性,适当调整饮食可能会减少胃食管反流的发生. | 涂蕾 侯晓华 | 2011 | 中华内科杂志2011，50，8： | 9 |
| 2 | 胃食管反流病症状谱及危险因素显示文摘目的:探讨胃食管反流病(gastroesophageal reflux disease,GERD)症状谱,分析与之相关的危险因素。方法:以南充市中心医院消化内科门诊及胃镜室确诊的GERD患者为病例组,以健康体检者及无烧心、反酸等典型症状且内镜检查为慢性浅表性胃炎者为对照组,采用问卷调查收集GERD患者就诊的主要症状,分析GERD的相关症状谱及危险因素。结果:共收集病例组370例,对照组347例。GERD症状谱系广泛、多样化,临床表现以烧心、反流症状为主,分别占84.05%和70.00%;RE组与NERD组患者主要相关症状发生率比较差异无统计学意义(P>0.05)。低教育水平、吸烟、喜高脂食物、便秘、肥胖、食管裂孔疝等可能是GERD的危险因素。结论:GERD以烧心、反流为主要表现,RE与NERD临床表现相似,吸烟等多种危险因素与GERD发病有关。 | 唐小波 陈杰 周晓晴 | 2013 | 川北医学院学报2013，28，6： | 9 |
| 3 | Efficacy and safety of Amla(Phyllanthus emblica L.) in non-erosive reflux disease:a double-blind,randomized,placebo-controlled clinical trial显示文摘Background: Gastroesophageal reflux disease(GERD) is one of the most common gastrointestinal complaints. GERD, caused by the reflux of stomach contents into the esophagus, leads to troublesome symptoms such as heartburn and regurgitation. It is classified into two types: erosive esophagitis,characterized by visible esophageal mucosa erosion in endoscopy, and non-erosive reflux disease(NERD). GERD is a chronic and recurrent disease that impairs the quality of life and imposes socioeconomic and therapeutic burdens to both patients and society.Objective: Due to the failure of the conventional treatments for GERD and to the traditional use of Amla(Phyllanthus emblica L.), in addition to beneficial effects shown in recent studies, we evaluated the safety and efficacy of Amla tablet for improvement of symptoms of patients with NERD.Design, setting, participants and interventions: We designed a double-arm, randomized, double-blind,placebo-controlled clinical trial. Sixty-eight patients who had classic symptoms of GERD(heartburn,regurgitation and epigastralgia) for at least three months before the start of the trial were randomized in two parallel groups. Patients in the Amla group received two 500 mg Amla tablets twice a day, after meals,for 4 weeks. In the control group, patients received placebo tablets similar to the Amla prescription.Main outcome measures: The patients were visited at baseline, and at the end of the 2 nd and 4 th weeks of intervention; their symptoms were measured on a frequency and severity scale for the symptoms of NERD,according to the quality of life in reflux-associated disease questionnaire.Results: Frequencies of heartburn and regurgitation in both groups of the study were significantly reduced after intervention(P < 0.001). Repeated measures logistic regression analysis showed that, in the Amla group, there was a more significant reduction in regurgitation frequency, heartburn frequency, regurgitation severity and heartburn severity during the study period, compared with the placebo group(P < 0.001).Conclusion: This randomized double-blind, placebo-controlled clinical trial demonstrated that Amla could reduce frequencies of heartburn and regurgitation and improve heartburn and regurgitation severity in patients with NERD. | Shahnaz Karkon Varnosfaderani Fataneh Hashem-Dabaghian Gholamreza Amin Mahbubeh Bozorgi Ghazaleh Heydarirad Esmaeil Nazem Mohsen Nasiri Toosi Seyed Hamdollah Mosavat | 2018 | Journal of Integrative Medicine2018，16，2： | 7 |
| 4 | 胃食管反流病与饮食因素的关系显示文摘 | 陈斌鸣 荆绪斌 | 2008 | 广东医学2008，29，3： | 7 |
| 5 | 影响胃食管反流病复发的饮食相关因素分析显示文摘 | 何雪云 何晓燕 陈永明 余方珍 | 2010 | 浙江中西医结合杂志2010，20，8： | 2 |
| 6 | Prevalence and risk factors of gastroesophageal reflux disease in Qashqai migrating nomads, southern Iran显示文摘AIM: To investigate the prevalence and risk factors of gastroesophageal re? ux disease (GERD) symptoms in Qashqai migrating nomads with a different life style in Fars province, southern Iran. METHODS: In summer 2006, 748 Qashqai migrating nomads aged 25 years or more were enrolled using a multiple-stage stratified cluster random sampling method. A questionnaire consisting of demographic characteristics, lifestyle and GERD symptoms (heartburn, regurgitation, chest pain, dysphagia, hoarseness and cough) as completed for each subject. RESULTS: The questionnaire was completed in 717 subjects. The prevalence rate of GERD, defined as reflux occurring at least one time per week in the preceding year, was 33% (237 subjects). The prevalence was higher in older individuals (36.0% vs 28.9%, P < 0.05) and in those with other gastrointestinal complaints (51.0% vs 27.8%, P < 0.001), but not different in obese and non-obese subjects. It was also higher in those consuming fruitsand vegetables more than once a week (36.2% vs 17.3%, P < 0.001). GERD had a positive correlation with smoking (42.1% vs 27.8%, P < 0.001), but a negative relation with non-alcoholic beverages. The association between GERD and non-steroidal antiinflammatory drugs (NSAIDs) consumption was also signifi cant (40.2% vs 25.4%, P < 0.001). CONCLUSION: The prevalence of GERD (33%) is very high in Qashqai migrating nomads which may be due to a lower socioeconomic and educational level of these people and difference in the life style. Older age, frequent consumption of fruits and vegetables, smoking and NSAIDs are risk factors for GERD in this population. | Ahmad Mostaghni Davood Mehrabani Farnaz Khademolhosseini Seyed Jalil Masoumi Fariba Moradi Najaf Zare Mehdi Saberi-Firoozi | 2009 | World Journal of Gastroenterology2009，15，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员