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1Resected case of eosinophilic cholangiopathy presenting with secondary sclerosing cholangitis显示文摘Eosinophilic cholangiopathy is a rare condition characterized by eosinophilic infiltration of the biliary tract and causes sclerosing cholangitis.We report a patient with secondary sclerosing cholangitis with eosinophilic cholecystitis.A 46-year-old Japanese man was admitted to our hospital with jaundice. Computed tomography revealed dilatation of both the intrahepatic and extrahepatic bile ducts,diffuse thickening of the wall of the extrahepatic bile duct,and thickening of the gallbladder wall.Under the diagnosis of lower bile duct carcinoma,he underwent pyloruspreserving pancreatoduodenectomy and liver biopsy. On histopathological examination,conspicuous fibrosis was seen in the lower bile duct wall.In the gallbladder wall,marked eosinophilic infiltration was seen.Liver biopsy revealed mild portal fibrosis.He was diagnosed as definite eosinophilic cholecystitis with sclerosing cholangitis with unknown etiology.The possible etiology of sclerosing cholangitis was consequent fibrosis from previous eosinophilic infiltration in the bile duct.The clinicopathological findings of our case and a literature review indicated that eosinophilic cholangiopathy could cause a condition mimicking primary sclerosing cholangitis(PSC).Bile duct wall thickening in patientswith eosinophilic cholangitis might be due to fibrosis of the bile duct wall.Eosinophilic cholangiopathy might be confused as PSC with eosinophilia.Fumihiko Miura Takehide Asano Hodaka Amano Masahiro Yoshida Naoyuki Toyota Keita Wada Kenichiro Kato Tadahiro Takada Junichi Fukushima Fukuo Kondo Hajime Takikawa 2009World Journal of Gastroenterology2009,15,11:4
2以肝损害为主要表现的嗜酸粒细胞增多症1例报告显示文摘1病例资料患者男性,59岁,退休。既往体健,主因“反复乏力、皮肤黄染1个月”于2019年12月4日入本院诊治。2019年11月患者无明显诱因出现乏力、食欲下降,伴腹胀、目黄、尿色加深,呈浓茶色,就诊于本院门诊,查肝功能:ALT 326 U/L、AST 78 U/L、ALP 360 U/L、GGT 643 U/L、TBil 75μmol/L、DBil 57μmol/L.吴昊 郑欣 朱磊 杨冬 2022临床肝胆病杂志2022,38,4:1
3反复发作的嗜酸粒细胞性胆管炎一例显示文摘患者男,71岁.因"巩膜及皮肤黄染1周"入院.无恶寒、发热,无腹痛、腹泻,不饮酒,无服药史.入院后实验室检查:WBC 10.2×10^9/L,嗜酸粒细胞(E)2.34×10^9/L,E%为 23.0%;凝血功能正常;ALT 915.6 U/L,AST 902.6 U/L,ALP 137.2 U/L,GGT 162.9 U/L,LDH 419.0 U/L,TB 282.8 μmol/L,DB 217.5 μmol/L,IB 65.3 μmol/L,ALB 37.9 g/L,PA 44.0 mg/L;肿瘤标志物AFP、CEA、CA153、CA724正常, CA19-9 47.64 U/ml;IgG 21.80 g/L,IgG4 0.32 g/L,IgM 2.62 g/L,IgE 896 U/ml,补体C3 0.8 g/L。吴坚芳 戴彦苗 徐宏伟 陆喜荣 许邹华 2017中华胰腺病杂志2017,17,2:0
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