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		题名	作者	年代	出处	被引量
	1	高强度聚焦超声对中晚期胰腺癌的止痛作用(英文)显示文摘Objective: The aim of this study was to evaluate the analgesic effect of high intensity focused ultrasound (HIFU) in patients with advanced pancreatic cancer. Methods: A total of 106 patients with advanced pancreatic cancer accompanied by abdominal pain were treated by HIFU. Pain intensities and quantities of morphine consumption before and after treatment were observed and compared. Results: The average pain intensities before treatment, and at d3, d7 after treatment were 5.80 ± 2.14, 2.73 ± 2.68, 2.45 ± 2.43 respectively (P < 0.01). Fifty-nine cases (55.7%) got to extremely effective, and 29 cases (27.4%) effective. Total efficient rate was 83.0 %. The average quantities of morphine consumption before and after treatment in the patients with grade III pain were 114.9 ± 132.5 mg, 16.8 ± 39.7 mg each person everyday respectively (P < 0.01). Conclusion: HIFU can relieve pain suffered by patients with pancreatic cancer effectively. It is a new adjuvant treatment for pancreatic cancer pain.	Xinjin Tan Jian Chen Li Ren Ruilu Lin Zailian Chen	2013	The Chinese-German Journal of Clinical Oncology2013，12，8：	0
	2	放疗对胰腺癌细胞种植瘤血管生成的影响(英文)显示文摘Objective: The aim of this study was to observe the effect of radiation on micro-vessel density (MVD) and vascular endothelial growth factor (VEGF) expression in an transplanted tumor of human pancreatic cancer in nude mice and to explore the role of radiotherapy on pancreatic cancer angiogenesis. Methods: After vaccinated pancreatic cancer PANC-1 cells, 20 nude mice were randomly divided into radiation group and control group. Radiation group received the radiation (dose of 20 Gy) and were killed 5 days later. The MVD and VEGF expression were determined by immunohistochemistry and then compared with the control group. Results: The number of MVD in the radiation group was significantly lower than that of the control group (8.30 ± 4.55 vs. 13.60 ± 4.28, P < 0.01). The optical density (OD) of VEGF in the radiation group was higher (2.11 ± 0.54 vs. 1.32 ± 0.61, P < 0.05) compared with the control group. Conclusion: The radiotherapy can reduce the number of vessels and increase the VEGF expression of human pancreatic cancer transplanted tumor in nude mice.	Shan Huang Hongbing Ma	2012	The Chinese-German Journal of Clinical Oncology2012，11，11：	0

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