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1An efficient synthesis of bis(indolyl)methanes and N,N'-alkylidene bisamides by Silzic under solvent free conditions显示文摘An operationally simple and green method for the synthesis of a wide range of bis(indolyl)methanes,and N,N'-alkylidene bisamides under mild conditions,with excellent yields using Silzic,has been developed.This improved method furnishes in good yields bis(indolyl)methanes derivatives starting from indole and aldehydes,or ketones,and N,N'-alkylidene bisamides derivatives starting from acetamide and aldehydes.The catalytic system was reused up to three times with the same efficiency.Hanan A.Soliman Ahmed Y.Mubarak Saad S.Elmorsy 2016Chinese Chemical Letters2016,27,3:4
2Potassium tert-Butanolate Promoted Reaction ofBenzaldehydes and Indoles: a New Strategy for Synthesis of Bis(indolyl)arylmethanes显示文摘t-BuOK-promoted synthesis of bis(indolyl)arylmethunes from aromatic aldehydes and indoles wasachieved. Substrates bearing different functional groups, especially groups which are sensitive to acidic media, arewell tolerated under the optimal condition, making this reaction particularly attractive for expanding the scope of thepresent protocols that provides bis(1H-indol-3-yl)arylmethanes.JIANG Chong LI Jue LU Guanghui ZHENG Yang YU Xinling LU Songyang HAI Li WU Yong 2017Chemical Research in Chinese Universities2017,33,2:0
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