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| 1 | ^(99)Tc^m-RBC SPECT显像在诊断颌面部脉管畸形的应用价值显示文摘目的:探讨单光发射型计算机断层(single-photo emission computed tomography)血池显像诊断颌面部脉管畸形的价值。方法:对40例临床上怀疑颌面部脉管畸形患者进行颌面部核素扫描,分别进行SPECT血池显像,以^(99)Tc^m-RBC为显像剂,观察不同类型脉管畸形血池显像情况,诊断结果与MRI比较进行χ~2检验。结果:^(99)Tc^m-RBC血池显像对颌面部静脉畸形诊断敏感度、特异性、准确性分别是97.50%%、100.00%、100.00%。^(99)Tc^m-RBC血池显像40例患者其中39例阳性(97.50%,39/40);1例显示假阴性(2.50%,1/40);MRI对颌面部静脉畸形诊断其中33例阳性(82.50%,33/40),7例为阴性(7.50%,7/40),^(99)Tc^m-RBC血池显像与MRI影像学对比检查经χ~2检验有统计学意义(χ~2=0.028,P<0.05)。不同类型脉管畸形血池显像出现在不同时相。结论:^(99)Tc^m-RBC血池显像诊断颌面部脉管畸形有良好的应用价值。 | 刘洪伟 黄承明 安林 | 2019 | 口腔医学研究2019，35，4： | 2 |
| 2 | An aqueous extract of Liu Wei Di Huang Wan alters the labeling of blood constituents with Technetium-99m显示文摘The Liu Wei Di Huang Wan is a formula of a traditional Chinese medicine that is used to treat asthma patients and has been shown to have several important properties,such as antioxidant and free radical scavenging activities.The influence of an extract of Liu Wei Di Huang Wan on the labeling of blood constituents with technetium-99m was investigated.Anticoagulated blood(Wistar rats) was incubated with the extract,stannous chloride and technetium-99m,as sodium pertechnetate.Samples were centrifuged and aliquots of plasma and blood cells were separated and precipitated with trichloroacetic acid,to obtain soluble and insoluble fractions of the blood constituents.The percentage of radioactivity(%ATI) in all the fractions was determined.The analysis of the results shows that the extract at the highest concentration used(70 mg/mL) decreased significantly(P<0.05) the %ATI(from 96.48 ± 1.19 to 54.46 ± 7.38) on blood cells compartment,(from 81.11 ± 4.15 to 61.33 ± 4.74) on insoluble fractions of blood cells and(from 65.91 ± 2.44 to 13.15 ± 3.62) on insoluble fractions of plasma.In conclusion,the results suggest that the substances present on this extract can alter this labeling process,probably due to(i) redox properties(antioxidant and chelator activities) and/or(ii) specific actions in the binding sites where the 99mTc would be bound on the blood constituents.As a consequence,precaution is suggested on the interpretation of the nuclear medicine results from performed with blood constituents labeled with 99m Tc in patients that have undertaken LWDHW,although the current findings were obtained in experimental animal models. | MATOS Vernica Soares de CARMO Fernanda Santos do DINIZ Claudia Leite NASCIMENTO Ana Lucia Rosa PEREIRA Márcia Oliveira FERNANDES Joelma Fonseca de Oliveira SANTOS-FILHO Sebastiao David MORENO Silvana Ramos Farias BERNARDO-FILHO Mario | 2013 | Chinese Science Bulletin2013，58，18： | 0 |
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