共被期刊论文引用了3次
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| 1 | 牛角瓜的研究动态显示文摘牛角瓜广泛分布于亚洲和非洲热带及亚热带地区,在云南主要分布于干热河谷区,具有药用、纤维、能源等开发利用价值,为不可多得的生态经济型植物。通过对牛角瓜国内外研究资料的分析,介绍牛角瓜在种质资源挖掘和利用、繁育技术、生物生态学、栽培技术、开发利用等方面的研究动态,展望其在药用、纤维、能源等领域的开发利用前景,分析牛角瓜在开发与研究中尚存在的问题,提出了研究方向,旨在为牛角瓜的资源开发及产业推广提供参考依据。 | 郑元 罗明灿 高柱 唐军荣 刘鹏 王连春 马焕成 刘惠民 | 2015 | 西南林业大学学报(自然科学)2015，35，5： | 9 |
| 2 | Toxicarioside A inhibits SGC-7901 proliferation,migration and invasion via NF-κB/bFGF signaling显示文摘AIM:To investigate the inhibitory role of toxicarioside A on the gastric cancer cell line human gastric cancer cell line(SGC-7901) and determine the underlying molecular mechanism.METHODS:After SGC-7901 cells were treated with toxicarioside A at various concentrations(0.5,1.5,4.5,9.0 μg/mL) for 24 h or 48 h,cell viability was determined by 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl2H-tetrazolium bromide assay,and the motility and invasion of tumor cells were assessed by the Transwell chamber assay.Immunofluorescence staining,reverse transcription polymerase chain reaction and Western blotting were performed to detect the expression of basic fibroblast growth factor(bFGF) and fibroblast growth factor receptor-1(FGFR1),and nuclear factorkappa B(NF-κB) activation was examined by electrophoretic mobility shift assay.RESULTS:The results showed that toxicarioside A was capable of reducing cell viability,inhibiting cell growth,and suppressing cell migration and invasion activities in a time-and dose-dependent manner in SGC-7901 cells.Further analysis revealed that not only the expression of bFGF and its high-affinity receptor FGFR1 but also the NF-κB-DNA binding activity were effectively blocked by toxicarioside A in a dose-dependent manner compared with the control group(P < 0.05 or P < 0.01).Interestingly,application of the NF-κB specific inhibitor,pyrrolidinedithiocarbamate(PDTC),to SGC-7901 cells significantly potentized the toxicarioside A-induced down-regulation of bFGF compared with the control group(P < 0.05).CONCLUSION:These findings suggest that toxicarioside A has an anti-gastric cancer activity and this effect may be achieved partly through down-regulation of NF-κB and bFGF/FGFR1 signaling. | Jun-Li Guo Shao-Jiang Zheng Yue-Nan Li Wei Jie Xin-Bao Hao Tian-Fa Li Li-Ping xia Wen-Li Mei Feng-Ying Huang Yue-QiongKong Qi-Yi He, Kun Yang Guang-Hong Tan Hao-Fu Dai | 2012 | World Journal of Gastroenterology2012，18，14： | 8 |
| 3 | 强心苷类抗癌作用研究进展显示文摘强心苷类物质可分为外源性强心苷类和内源性强心苷类。该文主要阐述了强心苷类的抗癌作用机制与其抑制Na+,K+-ATP酶、缺氧诱导因子-1、成纤维细胞生长因子、核转录因子及拓扑异构酶的活性,阻断雌激素受体,诱导细胞凋亡以及细胞毒作用相关;简要阐述了强心苷类对乳腺癌及前列腺癌等恶性肿瘤的作用效果以及内源性强心苷类与癌症的可能关系。 | 陈大朋 唐泽耀 熊永建 林原 | 2011 | 中国药理学通报2011，27，11： | 3 |
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