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1Neural differentiation of human placenta-derived mesenchymal stem cells following neural cell co-culture显示文摘We induced human placenta-derived mesenchymal stem cells(hPMSCs) to differentiate into neural cells by adding chemical reagents,despite the fact that toxic chemicals induce cell shrinkage or cytoskeletal formation,which does not represent a proper cell differentiation process.The present study established a co-culture system with hPMSCs and neural cells and analyzed the influence of neural cells on hPMSC differentiation in a co-culture system.hPMSCs were isolated and purified from human full-term placenta using collagenase digestion.Fetal neural cells were co-cultured with hPMSCs for 48 hours using the Transwell co-culture system.hPMSCs co-cultured with neural cells exhibited a slender morphology with a filament.After 96 hours,hPMSCs expressed neuron-specific enolase,which suggested that co-culture of hPMSCs and neural cells induced neural differentiation of hPMSCs.Nailong Yang Hongyan Zhang Xiaojuan Sun Lili Xu 2011Neural Regeneration Research2011,6,1:2
2人胎盘提取物药理作用研究进展显示文摘健康产妇胎盘提取物具有肝保护、抗炎、抗氧化、促进癌细胞凋亡、改善创伤和促进神经再生等作用,临床主要用于抗疲劳、慢性肝病和癌症辅助治疗等。本文对人胎盘提取物药理作用研究进展进行了综述。眭荣春 肖云 胡庭国 邓晓军 胡亚军 2021海峡药学2021,33,8:1
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